Results 71 to 80 of about 563,489 (286)

Nephron Patterning: Lessons from Xenopus, Zebrafish, and Mouse Studies

open access: yesCells, 2015
The nephron is the basic structural and functional unit of the vertebrate kidney. To ensure kidney functions, the nephrons possess a highly segmental organization where each segment is specialized for the secretion and reabsorption of particular solutes.
Audrey Desgrange, Silvia Cereghini
doaj   +1 more source

Inverse relationship between genetic diversity and epigenetic complexity [PDF]

open access: yes, 2008
Early studies of molecular evolution revealed a correlation between genetic distance and time of species divergence. This observation provoked the molecular clock hypothesis and in turn the ‘Neutral Theory’, which however remains an ...
Shi Huang
core   +3 more sources

Micro and Nanostructural Diversity of Lizard Osteoderm Capping Tissue in Relation to Mechanical Performance

open access: yesAdvanced Functional Materials, EarlyView.
This study shows that lizard osteoderm capping tissue is a hyper‐mineralized hydroxyapatite layer consistently covering the superficial osteoderm surface in those species studied here, yet it varies greatly in morphology, nanostructure, and mechanical performance across species.
Adrian Rodriguez‐Palomo   +10 more
wiley   +1 more source

The Upper Famennian Ketleri Formation of Latvia: new data on the fauna and flora from tide-dominated delta deposits in a seasonal climate [PDF]

open access: yesEstonian Journal of Earth Sciences
Combined sedimentological and palaeontological studies of the vertebrate fossil-bearing deposits of the Upper Devonian, Upper Famennian Ketleri Formation have provided new data on the sedimentary environment of the deposits, as well as on taxonomic and ...
Ervīns Lukševičs   +4 more
doaj   +1 more source

Functional characterization of a short peptidoglycan recognition protein from Chinese giant salamander (Andrias davidianus) [PDF]

open access: yes, 2017
This work was supported by the National Natural Science Foundation of China (Grant no. 31302221, 31172408 and 31272666) and Jiangsu Province (Grant no.
Chang, Mingxian   +8 more
core   +1 more source

MagPiezo: A Magnetogenetic Platform for Remote Activation of Endogenous Piezo1 Channels in Endothelial Cells

open access: yesAdvanced Functional Materials, EarlyView.
MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández   +7 more
wiley   +1 more source

Gentamicin‐Loaded Carbonate Apatite with Dual Antibacterial and Osteogenic Functions for Combating Surgical Site Infections

open access: yesAdvanced Healthcare Materials, EarlyView.
A bone substitute with gentamicin physically precipitated onto the surface of carbonate apatite exhibits prompt drug release, high bactericidal activity, and osteogenic capacity. Efficient antibacterial activity mitigates early postoperative neutrophil accumulation, the status of which may serve as a potential parameter for evaluating the antibacterial
Linghao Xiao   +6 more
wiley   +1 more source

3D‐Printed Titanium Implants with Bioactive Peptide‐Polysaccharide Scaffolds for Personalized Bone Reconstruction

open access: yesAdvanced Healthcare Materials, EarlyView.
Porous 3D‐printed titanium implants are made bioactive by integration with a supramolecular peptide‐hyaluronic acid nanofibrillar scaffold, without the addition of exogenous cells or growth factors. Uniform filling of the implant architecture promotes vascularized, spatially homogeneous bone regeneration, significantly enhancing osteogenesis throughout
Noam Rattner   +8 more
wiley   +1 more source

Travelling between Two Worlds: Complement as a Gatekeeper for an Expanded Host Range of Lyme Disease Spirochetes

open access: yesVeterinary Sciences, 2016
Evading innate immunity is a prerequisite for pathogenic microorganisms in order to survive in their respective hosts. Concerning Lyme disease spirochetes belonging to the Borrelia (B.) burgdorferi sensu lato group, a broad range of diverse vertebrates ...
Peter Kraiczy
doaj   +1 more source

An inconvenient misconception: Climate change is not the principal driver of biodiversity loss

open access: yesConservation Letters, 2022
The current perception that climate change is the principal threat to biodiversity is at best premature. Although highly relevant, it detracts focus and effort from the primary threats: habitat destruction and overexploitation.
Tim Caro   +4 more
doaj   +1 more source

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