Results 31 to 40 of about 6,568 (145)

Genetically predicted KIR2DS4 mediate the association between gut microbe K10 and osteoporosis fractures: A mediation Mendelian randomization study

PM&R, EarlyView.
Abstract Background Osteoporosis fractures pose a significant public health concern, leading to substantial morbidity and mortality rates. The emerging evidence on the potential link between gut microbiota, proteins, and osteoporosis fractures suggests a complex relationship that warrants further investigation.
Qiong Wang, Qing Kuang, Cheng Chen, Binru Wang, Wei Xiang, Xinming Li, Jianjiao Mou   +6 more
wiley   +1 more source

Patients', clinicians' and research's priorities on important outcomes in multiple myeloma: A mixed‐methods study

British Journal of Haematology, EarlyView.
Summary Research in multiple myeloma increasingly relies on surrogate end‐points to expedite approvals, yet these may not reflect patient priorities. We conducted a mixed‐methods study to identify outcomes valued by patients and clinicians and compare them with end‐points used in randomized controlled trials (RCTs).
Maria Mainou, Thomas Karagiannis, Eirini Pagkalidou, Aris Liakos, Panagiotis Malandrakis, Evdoxia Hatjiharissi, Sofia Chissan, Evdokia Mandala, Oliver Van Oekelen, Efthymia Vlachaki, Maria Papaioannou, Evangelos Terpos, Ghulam Rehman Mohyuddin, Apostolos Tsapas   +13 more
wiley   +1 more source

Balloon Kyphoplasty vs Vertebroplasty: A Systematic Review of Height Restoration in Osteoporotic Vertebral Compression Fractures

Journal of Pain Research, 2022
Nimesh Patel,1 David Jacobs,1 Jessin John,1 Mohamed Fayed,1 Lakshmi Nerusu,2 Marissa Tandron,2 William Dailey,2 Ricardo Ayala,2 Nabil Sibai,1,2 Patrick Forrest,1,2 Jason Schwalb,2,3 Rohit Aiyer1,2 1Department of Anesthesiology, Pain Management and ...
Patel N, Jacobs D, John J, Fayed M, Nerusu L, Tandron M, Dailey W, Ayala R, Sibai N, Forrest P, Schwalb J, Aiyer R   +11 more
doaj  

Unilateral Dual‐Plane Puncture Percutaneous Vertebroplasty Reduces Re‐Collapse in Osteoporotic Vertebral Compression Fractures by Advancing Cement Delivery

Orthopaedic Surgery, Volume 17, Issue 5, Page 1322-1331, May 2025.
Trajectory of the unilateral dual‐plane puncture. The sagittal CT scan after surgery clearly shows the puncture trajectory of the unilateral dual‐plane puncture. The bone cement simultaneously contacted both the upper and lower end plates. ABSTRACT Purpose Evaluate the efficacy of a novel unilateral dual‐plane puncture technique in improving bone ...
Huo‐Liang Zheng, Chang‐hai Liu, Lei‐Sheng Jiang, Xin‐Feng Zheng, Sheng‐Dan Jiang   +4 more
wiley   +1 more source

EVALUATION OF EFFECTIVENESS OF PERCUTANEOUS VERTEBROPLASTY IN COMPLEX TREATMENT OF OSTEOPOROSIS WITH PATHOLOGICAL VERTEBRAL FRACTURES

Travmatologiâ i Ortopediâ Rossii, 2016
The effectiveness of vertebroplasty in treatment of 84 patients with osteoporosis and pathological fractures of the vertebrae was evaluated. 68 patients of the first group were underwent a comprehensive conservative treatment, percutaneous vertebroplasty
D. S. Astapenkov
doaj   +1 more source

Ultrasound‐Triggered Gelation for Restoring Biomechanical Properties of Degenerated Functional Spinal Units

Advanced Healthcare Materials, Volume 15, Issue 7, 16 February 2026.
This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans, Anna P. Constantinou, Matthew J. Kibble, Valeria Nele, Daniel Reumann, Luca Bau, Sebastien J. P. Callens, James P. K. Armstrong, Nicolas Newell, Constantin C. Coussios, Molly M. Stevens, Michael D. Gray   +11 more
wiley   +1 more source

Hypofractionated Radiation Therapy for Pain Relief of Patients With Spinal Metastasis: A Real‐World Analysis

Cancer Reports, Volume 9, Issue 2, February 2026.
ABSTRACT Purpose Spinal metastases may cause pain, neurological compromise, paraplegia, and limb movement disorders; their management requires a comprehensive approach. Alongside systemic anti‐tumor therapies, focal interventions such as radiotherapy, bone‐modifying agents, and surgery are crucial for slowing disease progression and managing pain in ...
Lu Sun, Fan Luo, Yajuan Zhou, Xiyou Liu, Pingping Zhang, Dan Li, Yi Peng   +6 more
wiley   +1 more source

Percutaneous Vertebroplasty for Osteoporotic Compression Fractures Using Calcium Phosphate Cement

Journal of Orthopaedic Surgery, 2010
Purpose. To compare percutaneous transpedicular vertebroplasty using calcium phosphate cement (CPC) versus conservative treatment for osteoporotic vertebral fractures. Methods.
Shigeo Ishiguro, Yuichi Kasai, Akihiro Sudo, Koji Iida, Atsumasa Uchida   +4 more
doaj   +1 more source

Percutaneous vertebroplasty as therapy of vertebral fractures: results in a series of osteoporotic patients

Reumatismo, 2011
In the recent years, percutaneous vertebroplasty is available for the treatment of the vertebral fractures, primarily to relieve pain related to the lesion.
F. Cavallari, S. Vallone, L. Bernini, C.U. Manzini, C. Ferri   +4 more
doaj   +1 more source

A Polymethyl Methacrylate Bone Cement With Reduced Stress Concentration

Electron, Volume 4, Issue 1, February 2026.
PMMA/PLA/CNT composite bone cement with reduced stress concentration. ABSTRACT Polymethyl methacrylate (PMMA) bone cement is the earliest and most widely used in clinical applications. However, PMMA bone cement has high hardness and high modulus, which leads to secondary fracture of adjacent vertebrae. In this study, a PMMA/polylactic acid (PLA)/carbon
Lei Peng, Shengyu Zhou, Yunfa Dong, Yupei Han, Quan Li, Zhidong Cao, Zhengxue Quan   +6 more
wiley   +1 more source