Results 51 to 60 of about 22,479 (254)

Patients', clinicians' and research's priorities on important outcomes in multiple myeloma: A mixed‐methods study

open access: yesBritish Journal of Haematology, EarlyView.
Summary Research in multiple myeloma increasingly relies on surrogate end‐points to expedite approvals, yet these may not reflect patient priorities. We conducted a mixed‐methods study to identify outcomes valued by patients and clinicians and compare them with end‐points used in randomized controlled trials (RCTs).
Maria Mainou   +13 more
wiley   +1 more source

Unilateral Dual‐Plane Puncture Percutaneous Vertebroplasty Reduces Re‐Collapse in Osteoporotic Vertebral Compression Fractures by Advancing Cement Delivery

open access: yesOrthopaedic Surgery, Volume 17, Issue 5, Page 1322-1331, May 2025.
Trajectory of the unilateral dual‐plane puncture. The sagittal CT scan after surgery clearly shows the puncture trajectory of the unilateral dual‐plane puncture. The bone cement simultaneously contacted both the upper and lower end plates. ABSTRACT Purpose Evaluate the efficacy of a novel unilateral dual‐plane puncture technique in improving bone ...
Huo‐Liang Zheng   +4 more
wiley   +1 more source

The role of cement augmentation with percutaneous vertebroplasty and balloon kyphoplasty for the treatment of vertebral compression fractures in multiple myeloma: a consensus statement from the International Myeloma Working Group (IMWG)

open access: yesBlood Cancer Journal, 2019
Multiple myeloma (MM) represents approximately 15% of haematological malignancies and most of the patients present with bone involvement. Focal or diffuse spinal osteolysis may result in significant morbidity by causing painful progressive vertebral ...
C. Kyriakou   +13 more
semanticscholar   +1 more source

Effect of Functional Nasal Surgery on Craniofacial Pain: A Prospective Cohort Study

open access: yesThe Laryngoscope, Volume 136, Issue 4, Page 1649-1655, April 2026.
About 40% of patients presenting for nasal obstruction had craniofacial pain (CPF) preoperatively. In patients with nasal obstruction and CFP preoperatively, functional nasal surgery led to significant improvements in both nasal obstruction and CFP, and these improvements persisted at about 6 months postoperatively. ABSTRACT Objectives Functional nasal
John R. Craig   +4 more
wiley   +1 more source

EVALUATION OF EFFECTIVENESS OF PERCUTANEOUS VERTEBROPLASTY IN COMPLEX TREATMENT OF OSTEOPOROSIS WITH PATHOLOGICAL VERTEBRAL FRACTURES

open access: yesTravmatologiâ i Ortopediâ Rossii, 2016
The effectiveness of vertebroplasty in treatment of 84 patients with osteoporosis and pathological fractures of the vertebrae was evaluated. 68 patients of the first group were underwent a comprehensive conservative treatment, percutaneous vertebroplasty
D. S. Astapenkov
doaj   +1 more source

Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai   +3 more
wiley   +1 more source

Genetically predicted KIR2DS4 mediate the association between gut microbe K10 and osteoporosis fractures: A mediation Mendelian randomization study

open access: yesPM&R, Volume 18, Issue 4, Page 426-442, April 2026.
Abstract Background Osteoporosis fractures pose a significant public health concern, leading to substantial morbidity and mortality rates. The emerging evidence on the potential link between gut microbiota, proteins, and osteoporosis fractures suggests a complex relationship that warrants further investigation.
Qiong Wang   +6 more
wiley   +1 more source

Causes of Residual Back Pain at Early Stage After Percutaneous Vertebroplasty: A Retrospective Analysis of 1,316 Cases.

open access: yesPain Physician, 2019
BACKGROUND Percutaneous vertebroplasty (PVP) is now well accepted in the treatment of painful osteopathic vertebral compression fractures (OVCF), providing early pain relief and strengthening of the bone of the vertebrae.
Jun-song Yang   +9 more
semanticscholar   +1 more source

Improving the Quality and Efficiency of the Medicare Program Through Coverage Policy [PDF]

open access: yes, 2011
Outlines Medicare coverage and payment policy on new technologies and recommends changes that could help achieve the Triple Aim goals of enhancing the individual experience of care, improving population health, and reducing per capita costs of ...
Penny E. Mohr   +3 more
core  

Hydrogels for Bone Repair: Construction Strategies and Applications

open access: yesSmart Medicine, Volume 5, Issue 2, April 2026.
This review establishes an integrated framework for bone repair hydrogels, covering construction strategies from material selection to functional modification, mechanical and biological characterization, and diverse applications including defect repair, fracture healing, and smart responsive systems.
Miaomiao Wang   +7 more
wiley   +1 more source

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