Results 61 to 70 of about 9,427 (210)

Unraveling Chronic Pain: From Mechanisms and Risks to Diagnosis and Treatment

MedComm, Volume 7, Issue 4, April 2026.
Chronic pain arises through distinct molecular pathways categorized into nociceptive, neuropathic, and nociplastic types. Nociceptive pain begins with TRP channel activation in peripheral nociceptors, signaling via Aδ‐ and C‐fibers through the spinal dorsal horn and spinothalamic tracts to the brain, regulated by descending inhibition and involving ...
Xiaofeng Dai, Chongxiang Wang, Ping Jiang, Xiaopeng Mei   +3 more
wiley   +1 more source

In vivo temperature profile of intervertebral discs and vertebral endplates during vertebroplasty - An experimental study in sheep

, 2006
Study Design. Experimental study of temperature profiles during vertebroplasty.\ud \ud Objectives. To define accurate temperature profiles during vertebroplasty in an in vivo animal model.\ud \ud Summary of Background Data.
Williams, Richard, Krebs, Jorg, Thorpe, Paul, Goss, Benjamin G., Aebli, Nikolaus, Goss, Ben G.   +5 more
core   +1 more source

Genetically predicted KIR2DS4 mediate the association between gut microbe K10 and osteoporosis fractures: A mediation Mendelian randomization study

PM&R, Volume 18, Issue 4, Page 426-442, April 2026.
Abstract Background Osteoporosis fractures pose a significant public health concern, leading to substantial morbidity and mortality rates. The emerging evidence on the potential link between gut microbiota, proteins, and osteoporosis fractures suggests a complex relationship that warrants further investigation.
Qiong Wang, Qing Kuang, Cheng Chen, Binru Wang, Wei Xiang, Xinming Li, Jianjiao Mou   +6 more
wiley   +1 more source

Vertebroplasty and Kyphoplasty

, 2020
Vertebroplasty and ...
HK Kok (14446083), V Shah (7716221), RV Chandra (14446086), T Leslie-Mazwi (22009769), JA Hirsch (14457300), Hamed Asadi (13059153), Julian Maingard (13082895), NS Carter (19708483)   +7 more
core  

Biomechanical Effects of Cement Augmentation and Prophylactic Vertebroplasty on Adjacent Segment Stability in Multilevel Spinal Fusion: A Finite Element Analysis

Bioengineering
Background: Multilevel posterior spinal fusion to T10 often encounters complications such as screw loosening and proximal junctional kyphosis. Cement augmentation or prophylactic vertebroplasty is used to prevent these, but their biomechanical effects ...
Jae Won Shin, Dae Hyeon Kim, Ki Mun Kang, Tae Hyun Park, Yu Rim Oh, Sung Jae Lee, Byung Ho Lee   +6 more
doaj   +1 more source

Hydrogels for Bone Repair: Construction Strategies and Applications

Smart Medicine, Volume 5, Issue 2, April 2026.
This review establishes an integrated framework for bone repair hydrogels, covering construction strategies from material selection to functional modification, mechanical and biological characterization, and diverse applications including defect repair, fracture healing, and smart responsive systems.
Miaomiao Wang, Qianwei Su, Yuezhou Wu, Xiaoyi Liang, Fengjin Zhou, Yingying Jing, Zhanghua Li, Jiacan Su   +7 more
wiley   +1 more source

Chronic Painful Osteoporotic Vertebral Compression Fractures of Thoracolumbar Spine: Percutaneous Vertebroplasty versus Conservative Management among Egyptian Patients

Egyptian Spine Journal, 2015
Background Data: Vertebral augmentation procedures are widely used today in treating acute and subacute osteoporotic vertebral compression fractures (OVCFs).
Khaled Hassan, Mohammad El-Sharkawi
doaj   +1 more source

The Effectiveness of Percutaneous Vertebroplasty Is Determined by the Patient-Specific Bone Condition and the Treatment Strategy. [PDF]

PLoS ONE, 2016
PURPOSE:Vertebral fragility fractures are often treated by injecting bone cement into the collapsed vertebral bodies (vertebroplasty). The mechanisms by which vertebroplasty induces pain relief are not completely understood yet and recent debates cast ...
René P Widmer Soyka, Benedikt Helgason, Javad Hazrati Marangalou, Joop P van den Bergh, Bert van Rietbergen, Stephen J Ferguson   +5 more
doaj   +1 more source

MicroRNA‐128‐3p Deficiency Alleviates Bone Loss in Age‐Related Osteoporosis via Activation of Canonical Wnt Signaling

Aging Cell, Volume 25, Issue 4, April 2026.
Working model: MiR‐128‐3p inhibited the canonical Wnt signaling pathway by targeting Dvl2, resulting in reduced OB differentiation and age‐related osteoporosis. ABSTRACT MicroRNA‐128‐3p (miR‐128‐3p) has emerged as a crucial regulator of the aging process and age‐associated disorders. Recent research highlights the vital role of miR‐128‐3p in osteoclast
Gengyang Shen, Kun Chen, Qi Shang, Honglin Chen, Yu Liu, Guifeng Chen, Weicheng Qin, Jiahui He, Yuzhuo Zhang, Wenhua Zhao, Weiyu Qiu, Jingzhi Zhang, Hui Ren, Xiaobing Jiang   +13 more
wiley   +1 more source

Software for radionuclide vertebroplasty

, 2015
The problem of the software support for radionuclide vertebroplasty has been considered in general. Requirements to systems of preoperative preparation and postoperative analysis are described. The subject area (the vertebra operated on and its vicinity)
Kurachenko, Yu.A., Yu.G. Zabaryansky, А.А. Golovin, Levchenko, A.V., Golovin, А.А., Zabaryansky, Yu.G., N.K. Voznesensky, Yu.A. Kurachenko, Voznesensky, N.K., A.V. Levchenko   +9 more
core   +1 more source