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Results 121 to 130 of about 5,978,611 (274)

Engineered 3D Fibronectin‐Based Environments Modulate the Pathogenic Profile of Arthritic Synovial Fibroblasts

Advanced NanoBiomed Research, EarlyView.
Fibroblast behavior is shaped by the surrounding microenvironment, yet conventional culture systems often fail to capture disease‐relevant phenotypes. Here, platform‐dependent responses of healthy and arthritic synovial fibroblasts are examined across 2D and 3D culture systems. Distinct inflammatory and proliferative signatures emerge, highlighting how
Aneesah Khan +13 more
wiley +1 more source

Pelvic morphology and body size in relation to the preauricular sulcus: Evidence from medieval to modern Iberia

The Anatomical Record, EarlyView.
Abstract The preauricular sulcus has long been debated as a pelvic feature variably attributed to obstetric stress, ligamentous traction, and broader biomechanical processes. To clarify its determinants, we analyzed 409 adult individuals from three archeological and one early modern skeletal collection from the Iberian Peninsula, integrating graded ...
Rebeca García‐González +5 more
wiley +1 more source

Shallow vertex minors, stability, and dependence

Stability and dependence are model-theoretic notions that have recently proved highly effective in the study of structural and algorithmic properties of hereditary graph classes, and are considered key notions for generalizing to hereditary graph classes
Kim, Eunjung +2 more
core +1 more source

Outcomes of Capsular Plication as Part of Hip Arthroscopic Management for Surgically Identified Microinstability Are Comparable to Outcomes in Matched Controls

Arthroscopy, EarlyView.
Purpose To compare 2‐year minimum outcomes of hip arthroscopic management with capsular plication in patients with microinstability with propensity‐matched controls. Methods We searched primary hip arthroscopies undertaken between August 2009 and December 2020 from a single‐surgeon database, excluding those with lateral center‐edge angle <18°, for ...
Catherine J. Bacon +6 more
wiley +1 more source

Creating a graph model for the diagnosis of the traction motor commutator-brush unit considering thermal factors

Известия Томского политехнического университета: Инжиниринг георесурсов, 2017
Increasing of diagnosis accuracy of the technical condition and energy efficiency of the rolling stock traction motor is one of the current problems of the modern railway transport.
Viktor Vasilievich Kharlamov +3 more
doaj +2 more sources

Investigating Pompeii Subsoil Using Geomatics and Geophysics Merged Analyses

Archaeological Prospection, EarlyView.
ABSTRACT The archaeological site of Pompeii represents an exceptional context for the application of non‐invasive and integrated investigation methods aimed at enhancing the understanding of both exposed and buried remains. This study presents the results of multidisciplinary research conducted in the Palestra Grande site, a large and strategically ...
Valentina Santoro +9 more
wiley +1 more source

On structural controllability in complex networks with periodic switching topologies

Asian Journal of Control, EarlyView.
Abstract This paper investigates the structural controllability of complex networks with periodic switching topologies. First, several graph transformations that preserve structural controllability are demonstrated. Based on the n‐walk theory, a criterion is derived that determines structural controllability by analyzing only the joint graph within a ...
Jingrui Hou, Zhaohui Liu, Xinghuo Yu, Mahdi Jalili +3 more
wiley +1 more source

Comparative efficacy of GLP‐1 RA, tirzepatide and SGLT‐2 inhibitors in metabolic liver disease: A network meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aim Metabolic liver disease, including nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis, is a major cause of chronic liver dysfunction worldwide, creating an urgent need for effective treatments. This systematic literature review (SLR) and network meta‐analysis (NMA) systematically reviews and compares the efficacy and safety ...
Andrej Belančić +8 more
wiley +1 more source

Repeated intradermal lipopolysaccharide challenge responses in healthy volunteers: Implications for clinical pharmacology studies

British Journal of Clinical Pharmacology, EarlyView.
Aim Intradermal application of lipopolysaccharide (LPS), a Toll‐like receptor 4 agonist, induces a local inflammatory response and is used as a human challenge model to evaluate the pharmacodynamics of investigational medicinal products. While currently applied in a single, parallel‐group setting, alternative within‐subject designs involving repeated ...
Alexandra A. J. Sillé +12 more
wiley +1 more source

Cryo‐EM Analysis of Adenovirus Vector Reveals Purification Conditions Leading to Loss of Viral Fiber Proteins and Reduced Infectivity

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Vaccines and gene therapies require efficient delivery of genetic material to host cells. Viral vectors leverage viruses' ability to enter host cells to achieve this. Following the SARS‐CoV‐2 vaccine and novel gene therapies that utilize adenovirus vectors, there has been an increase in the demand for large‐scale production of vectors.
Betsy Widdicombe +7 more
wiley +1 more source

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