Results 41 to 50 of about 735,406 (199)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel   +3 more
wiley   +1 more source

Asymptotic Analysis of the Eigenvalues of a Laplacian Problem in a Thin Multidomain

open access: yes, 2006
We consider a thin multidomain of $R^N$, N>1, consisting of two vertical cylinders, one placed upon the other: the first one with given height and small cross section, the second one with small thickness and given cross section.
Gaudiello, Antonio, Sili, Ali
core   +3 more sources

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

open access: yesFEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

Multi‐institutional study on image quality for a novel CBCT solution on O‐ring linac

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Introduction This work presents a multi‐institutional study on image quality provided by a novel cone beam computed tomography (CBCT). The main goal is to investigate the consistency of imaging performance across multiple institutions.
Luis Agulles‐Pedrós   +11 more
wiley   +1 more source

Likelihood informed dimension reduction for inverse problems in remote sensing of atmospheric constituent profiles

open access: yes, 2018
We use likelihood informed dimension reduction (LIS) (T. Cui et al. 2014) for inverting vertical profile information of atmospheric methane from ground based Fourier transform infrared (FTIR) measurements at Sodankyl\"a, Northern Finland.
A Karion   +9 more
core   +1 more source

Matrix model and dimensions at hypercube vertices [PDF]

open access: yesTheoretical and Mathematical Physics, 2017
In hypercube approach to correlation functions in Chern-Simons theory (knot polynomials) the central role is played by the numbers of cycles, in which the link diagram is decomposed under different resolutions. Certain functions of these numbers are further interpreted as dimensions of graded spaces, associated with hypercube vertices.
Anton Morozov   +2 more
openaire   +4 more sources

Modelling of a double‐scattering proton therapy nozzle using the FLUKA Monte Carlo code and analysis of linear energy transfer in patients treated for prostate cancer

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background The dose‐averaged linear energy transfer (LETD) in proton therapy (PT) has in pre‐clinical studies been linked to the relative biological effectiveness (RBE) of protons. Until recently, the most common PT delivery method in prostate cancer has been double‐scattered PT, with LETD only available through dedicated Monte Carlo (MC ...
Rasmus Klitgaard   +7 more
wiley   +1 more source

Generalized Classical BRST Cohomology and Reduction of Poisson Manifolds

open access: yes, 1992
In this paper, we formulate a generalization of the classical BRST construction which applies to the case of the reduction of a poisson manifold by a submanifold.
B. Feigin   +14 more
core   +1 more source

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