Results 31 to 40 of about 558,175 (268)

Understanding Wind Characteristics Over Different Terrains for Wind Turbine Deployment

open access: yesMeteorological Applications
Understanding how complex orography influences lower atmospheric winds is essential for accurately characterizing wind conditions, especially in regions considered for wind energy development.
Rohan Kumar   +3 more
doaj   +1 more source

Multi-Dimensional Estimation of Leaf Loss Rate from Larch Caterpillar Under Insect Pest Stress Using UAV-Based Multi-Source Remote Sensing

open access: yesDrones
Leaf loss caused by pest infestations poses a serious threat to forest health. The leaf loss rate (LLR) refers to the percentage of the overall tree-crown leaf loss per unit area and is an important indicator for evaluating forest health.
He-Ya Sa   +11 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Seasonal dynamics and vertical distribution of ecosystem-level carbon stocks in different vegetation types of the Minjiang estuary wetland

open access: yesFrontiers in Marine Science
Coastal wetlands play a crucial role in the global carbon cycle and climate regulation by serving as significant reservoirs of ecosystem carbon stock. However, their carbon sequestration capacity is strongly influenced by vegetation types, as well as the
Yulong Chen   +11 more
doaj   +1 more source

Zooplankton abundance, species composition and ecology of tropical high-mountain crater lake Wonchi, Ethiopia

open access: yesJournal of Limnology, 2014
The highlands of Ethiopia represent some of the remnants of undisturbed aquatic ecosystems; they are however highly threatened by significant socio–economic developments and associated anthropogenic impacts. Lake Wonchi is one of the few remaining fairly
Fasil Degefu, Michael Schagerl
doaj   +1 more source

Vertically Exported Phytoplankton (< 20 µm) and Their Correlation Network With Bacterioplankton Along a Deep-Sea Seamount

open access: yesFrontiers in Marine Science, 2022
Phytoplankton have been observed to be widely distributed in the oceanic vertical water columns and have an important contribution to carbon sequestration via biological pump mechanism. However, in seamount areas with strong hydrodynamics, their vertical
Hanshuang Zhao   +13 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Experimental study on side friction distribution of caissons during sinking in water

open access: yesYantu gongcheng xuebao, 2019
A sinking simulation experiment on a deep and large caisson is carried out based on the main caisson of Shanghai-Nomtong Bridge. Through the analysis of the whole dynamic sinking, it is determined that the effective stress on the sidewall is affected by ...
CHU Jing-lei , MA Jian-lin , JIANG Bing-nan , LI Meng-hao , ZHANG Kai
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

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