Results 101 to 110 of about 996,517 (272)

AI‐Designed TREM1‐Targeted LYTAC Nanoparticles Reprogram the Neuroimmune Microenvironment in Traumatic Brain Injury

Advanced Science, EarlyView.
AI‐enabled de novo design of a TREM1 binder, integrated into a BBB‐crossing and macrophage‐targeted nanoplatform, enables TREM1 degradation and attenuates neuroinflammation, thereby promoting neuroprotection and tissue repair after traumatic brain injury. ABSTRACT Secondary neuroinflammation drives progressive damage after traumatic brain injury (TBI),
Yimin Huang, Yuan Liu, Huan Peng, Yu Ni, Zhengqiao Jiang, Chenxuan Yu, Xincheng Zhang, Huayu Kang, Yanchao Liu, Juan Chen, Kai Zhao, Lin Han, Xin Zou, Kai Shu, Xiaochuan Wang, Jian‐Zhi Wang, Ting Lei, Chao Gan, Jianfeng Liu, Huaqiu Zhang   +19 more
wiley   +1 more source

Ultrasound‐Triggered piRNA Delivery Using Biomimetic Phase‐Changeable Nanoparticles for Theranostics of Myocardial Infarction

Advanced Science, EarlyView.
A biomimetic ultrasound‐responsive piRNA delivery nanoparticle platform (piR‐NPs) enables targeted delivery and ultrasound (US)‐triggered release of piR‐1873 in infarcted myocardium. The released piR‐1873 suppresses Usp2‐mediated RIP1/RIP3/MLKL necroptosis, reduces myocardial injury and fibrosis, and promotes cardiac functional recovery, providing a ...
Yajun Zhang, Hongzhao Qi, Yanyan Yang, Feng Wang, Tiantian Han, Yanbei Lei, Xiaolu Li, Zhibin Wang, Hua Qu, Tao Yu, Pin Sun   +10 more
wiley   +1 more source

Decoupling Stable Cyclic Deformation From Defect Accumulation in Metals

Advanced Science, EarlyView.
Introducing amorphous nanoparticles into a metal matrix enables a cyclic deformation regime where strain hardening and defect accumulation are decoupled. These nanoparticles act as dislocation sinks and undergo reversible shear transformations, sustaining microstructural stability over millions of cycles.
Chenjun Ye, Shaofan Ge, Tian Yang, Leyi Tang, Kang Wang, Y. Morris Wang, Jun Ding, Zan Li, Di Zhang, En (Evan) Ma   +9 more
wiley   +1 more source

Sulfide‐Based Electrolytes for All‐Solid‐State Sodium Batteries

Advanced Energy Materials, EarlyView.
This review covers the structural features and synthesis strategies of sulfide‐based solid electrolytes, as well as critical challenges related to conductivity, interfacial and moisture stability, and scaling‐up for practical application in Sodium‐based All Solid‐State Batteries.
Han Yang, Luca Weckelmann, Baolin Wu, Chih‐Long Tsai, Luc Raijmakers, Rüdiger‐A. Eichel, Anna Windmüller   +6 more
wiley   +1 more source

Real‐Time Multicolor Fluorescence Microscopy via Cross‐Channel Acquisition and Deep‐Learning‐Based Inference

Advanced Intelligent Discovery, EarlyView.
Sequential multicolor fluorescence imaging in dynamic microsystems is constrained by acquisition speed and excitation dose. This study introduces a real‐time framework to reconstruct spectrally separated channels from reduced cross‐channel acquisitions (frames containing mixed spectral contributions).
Juan J. Huaroto, Yuxin Jin, Nicholas Roy, Sarthak Misra   +3 more
wiley   +1 more source

Structure Analysis and Optimization of DGMC-16 Rail Grinding Wagon Frame

机车电传动, 2016
Taking the frame of DGMC-16 rail grinding wagon as studying object, the finite element method was adopted to calculate the longitudinal loads, judge the weak locations of frame for local optimization, and calculate the strength under different operation ...
Deng Ting, Zhu Shichang, Huang Zhihui, Zhang Linghong   +3 more
doaj  

Comparative Performance of Poly(Vinyl Alcohol)/Chitosan Hydrogels Reinforced With Kraft Lignin and Kraft Lignin Nanoparticles

Journal of Applied Polymer Science, EarlyView.
The use of kraft lignin and kraft lignin nanoparticles in poly(vinyl alcohol)/chitosan hydrogels was comprehensively compared. The results showed that a higher loading of lignin nanoparticles than bulk kraft lignin could be incorporated while maintaining favorable hydrogel properties, leading to improved overall performance. ABSTRACT The development of
Siriream Teapaibool, Pedram Fatehi
wiley   +1 more source

Strain‐Tunable Photoluminescence From Ge Quantum Dots on Si Nanotips for CMOS‐Compatible Photonics

Advanced Physics Research, EarlyView.
This work studies strain in Ge quantum dots grown on Si nanotips using photoluminescence, X‐ray diffraction, and band structure calculations. It shows how emission changes with dot size, evaluates strain in the dot and substrate, and explains the role of direct and indirect transitions in the optical behavior.
Diana Ryzhak, Johannes Aberl, Enrique Prado‐Navarrete, Lada Vukušić, Oliver Skibitzki, Petr Klenovský, Marvin Hartwig Zoellner, Markus Andreas Schubert, Moritz Brehm, Davide Spirito, Giovanni Capellini   +10 more
wiley   +1 more source

Integrated microanatomy and microstructure of the maxillary tooth plate reveal a reinforced feeding system and tougher diet in Late Triassic Hyperodapedontinae (Rhynchosauria, Archosauromorpha)

The Anatomical Record, EarlyView.
Abstract Hyperodapedontine rhynchosaurs possessed a unique oral apparatus, long interpreted as an adaptation for processing abrasive and resistant plant material. However, the microanatomical and histological evidence supporting this interpretation remains poorly documented.
Caio A. Scartezini, Pedro L. B. Pruciano, Brodsky D. M. Farias, Marina B. Soares   +3 more
wiley   +1 more source

Three‐dimensional digital analysis of musteloid masticatory muscle architecture

The Anatomical Record, EarlyView.
Musteloids span an enormous breadth of dietary modes within a single superfamily. In this study, we utilize digital dissection techniques to reconstruct the internal 3D anatomy of muscles within the musteloid feeding apparatus, and explore how dietary specializations might alter the size, orientation, and curvature of fascicles therein.
Cassidy E. Davis, Edwin Dickinson, Madison Manzo, Ashley R. Deutsch, Jillian S. Davis, Michael C. Granatosky, Adam Hartstone‐Rose   +6 more
wiley   +1 more source