Results 101 to 110 of about 1,030 (222)

Ranavirus ecology in common frogs (Rana Temporaria) from United Kingdom: transmission dynamics, alternate hosts and host-strain interactions.

, 2009
PhDThe ranaviruses (Family: Iridoviridae) are a group of emerging pathogens in amphibians. Ranavirus(es) were introduced to the UK in the late 1980s and have been associated with mass mortality events in common frogs (Rana temporaria) in south east ...
Duffus, Amanda Linda Jean
core  

Global Properties of Infectious Disease Models with Nonlinear Incidence [PDF]

, 2007
We consider global properties for the classical SIR, SIRS and SEIR models of infectious diseases, including the models with the vertical transmission, assuming that the horizontal transmission is governed by an unspecified function f(S,I).
Korobeinikov, Andrei
core   +1 more source

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

Advanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang, Yanling Gou, Huiyan Zhang, Hongli Wang, Beidi Wang, Jinming Liu, Yingying Cao, Ruru Bai, Yuxin Zhao, Xu Han, Chao Feng, Xin Huang, Zongfeng Zhang   +12 more
wiley   +1 more source

Thermostable Bioluminescent Intercalating Dyes for Real‐Time, Integrated Nucleic Acid Amplification and Detection

Angewandte Chemie, EarlyView.
We present a bioluminescent diagnostic platform that integrates DNA amplification and detection in a single step. The engineering of thermostable luciferase‐intercalating dye conjugates and controlled release of caged luciferin substrates enable real‐time, detection of attomolar concentrations of viral DNA within 30 min.
Yosta de Stigter, Harmen J. van der Veer, Sterre de Lignie, Robbert J. de Haas, Renko de Vries, Joost P. H. Schoeber, Anne J. M. Loonen, Adriaan J. C. van den Brule, Maarten Merkx   +8 more
wiley   +2 more sources

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

Advanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai, Huan Yu, Zihan Ni, Kan Chen, I‐Chen Tsai, Zeyu Bao, Shuo Sun, Weichang Li, Yunhua Chen, Qiong Xu   +9 more
wiley   +1 more source

Prevention of perinatal Group B streptococcal disease : a public health perspective [PDF]

Group B streptococcus is a leading cause of serious neonatal infection. Most neonatal GBS infections can be prevented through the use of intrapartum antimicrobial prophylaxis in women who are at increased risk for transmitting the infection to their ...
Centers for Disease Control (U.S.). Epidemiology Program Office.
core  

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

Advanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu, Yajing Liu, Shuman Wang, Xiaoming Bai, Luyun Zhang, Yuwei Liu, Zhiwen Fu, Chen Shi   +7 more
wiley   +1 more source

Effect of single-dose anthelmintic treatment during pregnancy on an infant's response to immunisation and on susceptibility to infectious diseases in infancy: a randomised, double-blind, placebo-controlled trial. [PDF]

, 2011
BACKGROUND: Helminth infections affect the human immune response. We investigated whether prenatal exposure to and treatment of maternal helminth infections affects development of an infant's immune response to immunisations and unrelated infections ...
Webb, Emily L, Mawa, Patrice A, Bukusuba, Joseph, Patrice A Mawa, Jacqueline Kyosiimire-Lugemwa, Bridget Nanteza, Alison M Elliott, Nampijja, Margaret, Hellen Akurut, Elliott, Alison M, Robert Tweyongyere, Kizito, Dennison, Moses Muwanga, Mpairwe, Harriet, Kizindo, Robert, Namujju, Proscovia B, Tweyongyere, Robert, Akello, Miriam, Ameke, Christine, Alice Namatovu, Ndibazza, Juliet, Harriet Mpairwe, Nabulime, Juliet, Miriam Akello, Kyosiimire-Lugemwa, Jacqueline, Akurut, Hellen, Kizza, Moses, Muhangi, Lawrence, Lawrence Muhangi, Kihembo, Macklyn, Proscovia B Namujju, Whitworth, James AG, Robert Kizindo, Margaret Nampijja, Nancy Lyadda, Juliet Nabulime, Macklyn Kihembo, Woodburn, Patrick W, Emily L Webb, Nanteza, Bridget, Muwanga, Moses, Joseph Bukusuba, Patrick W Woodburn, Moses Kizza, Namatovu, Alice, Lyadda, Nancy, Dennison Kizito, Christine Ameke, Juliet Ndibazza, James AG Whitworth   +49 more
core   +1 more source

Eco‐Geography Reverses Dominant AMR Reservoirs in Klebsiella pneumoniae: Integron‐Rich Mobilomes and Cross‐Niche Connectivity

Advanced Science, EarlyView.
Dominant antimicrobial resistance reservoirs in Klebsiella pneumoniae vary across eco‐geographic settings rather than following a universal pattern. Integrated One Health and global genomic analyses show that lineage structure, integron load, and cross‐niche connectivity shape whether AMR burden accumulates primarily in human or nonhuman compartments ...
Hui Lin, Biao Tang, Hao Xu, Jiajie Qian, Feifan Shi, Junhui Zhao, Xiaorui Mao, Xiaohe Hu, Ruishan Liu, Wenhong Liu, Xiawei Jiang, Beiwen Zheng, Guoping Zhao   +12 more
wiley   +1 more source

Integrated Serologic Surveillance of Population Immunity and Disease Transmission [PDF]

, 2018
Antibodies are unique among biomarkers in their ability to identify persons with protective immunity to vaccine-preventable diseases and to measure past exposure to diverse pathogens. Most infectious disease surveillance maintains a single-disease focus,
Patrick J. Lammie, Priest, Jeffrey W, Jeffrey W. Priest, Lammie, Patrick J, Benjamin F. Arnold, Heather M. Scobie, Scobie, Heather M, Arnold, Benjamin F   +7 more
core   +1 more source