Results 181 to 190 of about 531,046 (373)

Effects of F-1394, an Acyl-CoA:Cholesterol Acyltransferase (ACAT) Inhibitor, on ACAT Activity in HepG2 Cells and on Hepatic Secretion of Lipids in Triton WR-1339-Induced Hyperlipidemic Rats: Possible Role of Hepatic ACAT in Very Low Density Lipoprotein Secretion

, 1998
Katsumi Aragane, Jun Kusunoki, Tetsuya Kitamine, Tetsuaki Yamaura, Haruo Ohnishi   +4 more
openalex   +1 more source

Parallel Genome‐Wide CRISPR Screens Reveal SORL1 and ZFYVE19 as Sequential Host Determinants of Salmonella Infection

Advanced Science, EarlyView.
To distinguish how Salmonella invades cells vs how it survives long‐term, a parallel CRISPR screening platform is developed. This approach reveals the host proteins that the bacterium exploits at different stages of infection. The study identifies SORL1 as a novel host factor for invasion and demonstrates that blocking it with an antibody effectively ...
Sehee Yun, Seoyeon Kim, Seonggyu Kim, Minsoo Noh, Dae‐Kyum Kim, Eun‐Jin Lee, Hunsang Lee   +6 more
wiley   +1 more source

Electronegative very-low-density lipoprotein induces brain inflammation and cognitive dysfunction in mice. [PDF]

Sci Rep, 2021
Lin YS, Liu CK, Lee HC, Chou MC, Ke LY, Chen CH, Chen SL.   +6 more
europepmc   +1 more source

An apo-E-free very low density lipoprotein enriched in phosphatidylethanolamine in human plasma.

, 1986
P E Fielding, C J Fielding
openalex   +1 more source

Enhanced lipoprotein lipase secretion from human monocyte-derived macrophages caused by hypertriglyceridemic very low density lipoproteins. [PDF]

, 1989
Shun Ishibashi, Natsuko Mori, Toshio Murase, Hitoshi Shimano, T Gotohda, Masanobu Kawakami, Y. Akanuma, Fumimaro Takaku, N Yamada   +8 more
openalex   +1 more source

A Novel CYP2E1 Inhibitor, 4‐Methyl‐5‐Acetylthiazole (Q11), Alleviates Obesity Via Modulating Adipose Inflammation and Mitochondrial Dysfunction

Advanced Science, EarlyView.
Obesity involves chronic inflammation and mitochondrial dysfunction. This study identifies cytochrome P450 2E1 (CYP2E1) as a novel inflammatory target in adipose tissue. Its activity increases in obese mice and correlates with inflammation and mitochondrial impairment.
Jinhuan Qiu, Liyuan Gao, Liyang Wang, Xueke Wang, Lin Jia, Mengyan Deng, Liming Tang, Qiang Wen, Na Gao, Haiwei Xu, Hailing Qiao   +10 more
wiley   +1 more source

Impaired Very-Low-Density Lipoprotein catabolism links hypoglycemia to hypertriglyceridemia in Glycogen Storage Disease type Ia. [PDF]

J Inherit Metab Dis, 2021
Hoogerland JA, Peeks F, Hijmans BS, Wolters JC, Kooijman S, Bos T, Bleeker A, van Dijk TH, Wolters H, Gerding A, van Eunen K, Havinga R, Pronk ACM, Rensen PCN, Mithieux G, Rajas F, Kuipers F, Reijngoud DJ, Derks TGJ, Oosterveer MH.   +19 more
europepmc   +1 more source

Proteomic Analysis of the Very Low Density Lipoprotein (VLDL) transport vesicles

, 2012
Rahimin Affandi Abdul Rahim, Erika Nafi‐valencia, Shaila Siddiqi, Riyaz Basha, Chukwuemeka C. Runyon, Shadab A. Siddiqi, Shadab A. Siddiqi, Shadab A. Siddiqi   +7 more
openalex   +2 more sources

A Novel 10‐Protein Score for Liver Fat Content Predicts Cardiovascular‐Kidney‐Metabolic Disease Risk

Advanced Science, EarlyView.
A novel 10‐protein plasma score precisely quantifies liver fat, outperforming the fatty liver index. It robustly predicts the risk of numerous cardiovascular‐kidney‐metabolic diseases and integrates with genetic data for precision prevention, offering a practical alternative to magnetic resonance imaging (MRI). Abstract Liver fat content (LFC) is a key
Xiaoqin Gan, Yuanxiu Wei, Yiting Wu, Xinyue Su, Gangling Wang, Sisi Yang, Ziliang Ye, Yanjun Zhang, Hao Xiang, Yu Huang, Yiwei Zhang, Yuanyuan Zhang, Xianhui Qin   +12 more
wiley   +1 more source

β-migrating very-low-density lipoproteins and chylomicron remnants bind to rat liver hepatocytes at a low-density-lipoprotein-receptor-independent site (the remnant receptor) [PDF]

, 1995
J C Van Berkel, A H Voorschuur, Johan Kuiper   +2 more
openalex   +1 more source