Results 1 to 10 of about 67,544 (271)
VLDL receptor gene therapy for reducing atherogenic lipoproteins [PDF]
Molecular Metabolism, 2023 Over the past 40 years, there has been considerable research into the management and treatment of atherogenic lipid disorders. Although the majority of treatments and management strategies for cardiovascular disease (CVD) center around targeting low-density lipoprotein cholesterol (LDL-C), there is mounting evidence for the residual CVD risk attributed
Krauss, Ronald M +4 more
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Journal of Atherosclerosis and Thrombosis, 2017 Very low-density lipoprotein (VLDL) receptor is a member of the low-density lipoprotein (LDL) receptor family. It binds triglyceride rich lipoprotein (TGRL) but not LDL, because it recognizes apolipoprotein (apo)E only but not apoB. The VLDL receptor functions as a peripheral lipoprotein receptor in concert with lipoprotein lipase (LPL) in heart ...
Sadao Takahashi
exaly +4 more sources
Postprandial lipoprotein metabolism: VLDL vs chylomicrons [PDF]
Clinica Chimica Acta, 2011 Since Zilversmit first proposed postprandial lipemia as the most common risk of cardiovascular disease, chylomicrons (CM) and CM remnants have been thought to be the major lipoproteins which are increased in the postprandial hyperlipidemia. However, it has been shown over the last two decades that the major increase in the postprandial lipoproteins ...
Nakajima, Katsuyuki +11 more
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Scavenger receptor BI facilitates the metabolism of VLDL lipoproteins in vivo [PDF]
Journal of Lipid Research, 2008 Scavenger receptor class B type I (SR-BI) functions as an HDL receptor that promotes the selective uptake of cholesteryl esters (CEs). The physiological role of SR-BI in VLDL metabolism, however, is largely unknown. SR-BI deficiency resulted in elevated VLDL cholesterol levels, both on chow diet and upon challenge with high-cholesterol diets.
Miranda Van Eck +6 more
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The Differential Effects of HDL Subpopulations on Lipoprotein Lipase (LPL)-Mediated VLDL Catabolism [PDF]
Biomedicines, 2021 High-density lipoprotein (HDL) subpopulations functional assessment is more relevant for HDL anti-atherogenic activity than cholesterol level. The aim of the study was to assess the impact of HDL-2 and HDL-3 on lipoprotein lipase (LPL)-mediated very-low-density lipoprotein (VLDL) catabolism related to hypertriglyceridemia development.
Ewa Wieczorek +5 more
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Hepatic Golgi lipoproteins: precursors to plasma lipoproteins in hypercholesterolemic rats
Journal of Lipid Research, 1982 Two classes of nascent lipoproteins can be isolated from Golgi apparatus-rich fractions of liver from hypercholesterolemic rats. Golgi very low density lipoproteins (VLDL, d less than 1.006 g/ml) are enriched in cholesteryl esters and are similar in many
L L Swift, P D Soulé, V S LeQuire
doaj +1 more source
Journal of Lipid Research, 1973 The ability of rat intestine and liver to synthesize the various apoproteins of plasma lipoproteins was investigated. After the individual isolated organs were perfused with blood containing [3H]lysine, chylomicrons plus very low density lipoproteins ...
Herbert G. Windmueller +2 more
doaj +1 more source
Tikrit Journal of Pure Science, 2019 This study has been acomblished between December 2016 and September 2017 which included 70 patients with chronic renal failure who attended at Al-yarmuke teaching hospital in Baghdad with25 healthy individual as control.
Noor H. Ali +2 more
doaj +1 more source
Effect of very low-density lipoproteins on lipid transfer in incubated serum
Journal of Lipid Research, 1965 Incubation of human serum solutions low in glyceride content for 16 hr resulted in a net increase of cholesterol esters in all three major human serum lipoprotein classes, namely the very low-density lipoproteins of d < 1.006 (VLDL), low-density ...
A.V. Nichols, L. Smith
doaj +1 more source
Emerging Evidence of Pathological Roles of Very-Low-Density Lipoprotein (VLDL)
International Journal of Molecular Sciences, 2022 Embraced with apolipoproteins (Apo) B and Apo E, triglyceride-enriched very-low-density lipoprotein (VLDL) is secreted by the liver into circulation, mainly during post-meal hours. Here, we present a brief review of the physiological role of VLDL and a systemic review of the emerging evidence supporting its pathological roles.
Jih-Kai Huang, Hsiang-Chun Lee
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