Results 161 to 170 of about 380,048 (349)
The Multitarget Compound ZLY032 Achieves Treatment of Chronic Wounds
ZLY032, a dual free fatty acid receptor 1/peroxisome proliferator‐activated receptor δ agonist, accelerates wound healing in normal/diabetic/methicillin‐resistant Staphylococcus aureus‐infected models by promoting angiogenesis, reducing inflammation, and exhibiting antibacterial activity via argininosuccinate lyase targeting, with demonstrated efficacy
Manyu Gong+27 more
wiley +1 more source
Methylation at CPT1A locus is associated with lipoprotein subfraction profiles[S]
Lipoprotein subfractions help discriminate cardiometabolic disease risk. Genetic loci validated as associating with lipoprotein measures do not account for a large proportion of the individual variation in lipoprotein measures.
Alexis C. Frazier-Wood+9 more
doaj
Precursor-Product Relationship between Pools of Very Low Density Lipoprotein Triglyceride [PDF]
Philip J. Barter, Paul J. Nestel
openalex +1 more source
Elevated free testosterone levels and reduced very low-density lipoprotein levels in men with lifelong premature ejaculation: a preliminary study. [PDF]
Zhao J+5 more
europepmc +1 more source
SUMOylation is a Translatable Target in Hypoxic MNPs Regulating Retinal Vasculopathy
During ischemic retinopathy/retinal vasculopathy, UBC9‐mediated SUMOylation in retinal macrophages enhances their pro‐angiogenic capacity via hypoxia‐induced SUMOylation of FUS at K327/K502. This modification suppresses FUS binding to the Vegfa mRNA 3’UTR, stabilizing transcripts and facilitating VEGFA production. Targeting UBC9 inhibition can serve as
Zheng Zhong+9 more
wiley +1 more source
Transfer of very low density lipoprotein from hen plasma into egg yolk [PDF]
G. Holdsworth+2 more
openalex +1 more source
B‐OMVs, nanoscale vesicles derived from BCG, are identified as effective and safe inducers of trained immunity that protect against sepsis. Through TLR2‐mediated metabolic and epigenetic reprogramming of hematopoietic stem cells, B‐OMVs enhance inflammatory response and phagocytic activity.
Yuan Gong+16 more
wiley +1 more source
Fixed-time and continuous assays of very-low-density lipoprotein secretion rate from rat liver: mean vs. instantaneous velocity. [PDF]
Daneshnia K, Rasouli M.
europepmc +1 more source