Results 121 to 130 of about 540,009 (216)

An Overview of Liquid Chromatography–Mass Spectrometry (LC–MS) Methods for the Quantification of Antibody‐Drug Conjugates

open access: yesBiomedical Chromatography, Volume 40, Issue 2, February 2026.
ABSTRACT Antibody‐drug conjugates (ADCs) are innovative drugs composed of cytotoxic molecules (payload) linked to antibodies, that selectively target and kill cancer cells upon internalization. In vivo, ADCs exist as intact molecules, naked antibodies, or released, unconjugated (linker‐)payload.
Pauline L. M. Buitelaar   +4 more
wiley   +1 more source

Bletilla striata polysaccharide-coated andrographolide nanomicelles for targeted drug delivery to enhance anti-colon cancer efficacy

open access: yesFrontiers in Immunology
BackgroundVitamin E, which is also known as tocopherol, is a compound with a polyphenol structure. Its esterified derivative, Vitamin E succinate (VES), exhibits unique anticancer and healthcare functions as well as immunomodulatory effects.
Zhongqun Yue   +13 more
doaj   +1 more source

The impact of B‐cell reconstitution on mRNA vaccine responses in allogeneic stem cell transplant recipients

open access: yesClinical &Translational Immunology, Volume 15, Issue 2, 2026.
We characterised B‐cell responses to vaccination in allogeneic haematopoietic stem cell transplant (alloHCT) recipients. While mRNA prime‐boost vaccination stimulated expansion of vaccine‐specific B cells to affinity mature in a majority of alloHCT recipients, responses were variable and seemingly restricted by the presence of immature B‐cell ...
Fredrika Hellgren   +24 more
wiley   +1 more source

İttihat ve terakki: Zihniyet ve siyaset

open access: yes, 2018
In the Ottoman Empire, a new mindset became a phenomenon, which created awareness and was realized, following the change/transition caused by the Tanzimat reform era. The main aim of this work is to determine, in the Unionist tradition aspect, the intellectual and philosophical actors of this new mindset in the Ottoman Empire, reveal the ideological ...
openaire   +3 more sources

Exploring Body‐Specific Associations in Swipe Gestures: A Study on Hand Dominance and Emotional Valence

open access: yesInternational Journal of Psychology, Volume 61, Issue 1, February 2026.
ABSTRACT The Body‐Specificity Hypothesis suggests that the area around the dominant hand is perceived positively, contrasting with a negative perception around the non‐dominant hand. Given the pervasive use of interactive technologies, our study aimed to investigate body‐specific associations in real‐world settings, examining whether these are ...
Marta Maisto   +3 more
wiley   +1 more source

Establishing Immune Correlates of Protection Against Respiratory Syncytial Virus Infection to Accelerate Vaccine Development: A Model‐Based Meta‐Analysis

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT The objectives of this study were to quantify the relationship between vaccine‐induced immunogenicity responses and the protection against respiratory syncytial virus (RSV) infection‐related clinical outcomes, and to evaluate immunogenicity as a surrogate marker for vaccine efficacy (VE) to accelerate RSV vaccine development.
Yushi Kashihara   +5 more
wiley   +1 more source

Signal Processing for the Cluster Wideband Data Burst Mode

open access: yesJournal of Geophysical Research: Space Physics, Volume 131, Issue 2, February 2026.
Abstract The Wideband Data instrument is part of the Cluster spacecraft Wave Experiment Consortium. Its primary data path is a direct connection to the spacecraft data handling system providing real time downlink to the ground stations of the Deep Space Network and Panska Ves Observatory.
K. H. Yearby   +2 more
wiley   +1 more source

¿Qué ves? ¿Qué ves cuando me ves? Confianza institucional y Gobierno Abierto

open access: yesRevista Española de la Transparencia, 2018
En las políticas públicas el ejercicio de definir un objeto de intervención o un resultado o un impacto es altamente relevante en la medida que marca los límites de lo posible, deseable y realizable. En este trabajo se problematiza el contenido que se da
Cecilia Güemes
doaj  

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