Results 111 to 120 of about 102,829,138 (255)

Vesicle-Associated Membrane Proteins/VAMP Isoforms Orchestrate Platelet Cargo Trafficking [PDF]

Platelets are crucial to maintaining the vascular microenvironment. Upon vascular injury, they release cargo contents from their granules. These molecules, either made by platelets themselves or endocytosed from the blood, influence various processes ...
Whiteheart, Sidney W., Joshi, Smita, Begley, Jessie, Gibson, Cameron, McFarland, Jack, Chanzu, Harry, Wagner, Aleah, Mohammadmoradi, Shayan   +7 more
core  

Analysis of outer membrane vesicle associated proteins isolated from the plant pathogenic bacterium pv. campestris-2

, 2011
He brackets with numeration indicate the sections taken from the gel for tryptic digestion. (B) Protein profiles of OMVs isolated from cultures grown in M9 medium and the outer membrane (OM) fraction prepared from the same culture.Copyright information ...
Vishaldeep K Sidhu (86201), Frank-Jörg Vorhölter (86202), Karsten Niehaus (34530), Steven A Watt (86203)   +3 more
core   +1 more source

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan, Praveen Velammal, Kanmani Muthiah, Madhu Jatty, Christopher Adams   +4 more
wiley   +1 more source

Mover is peripherally associated with synaptic vesicle membranes.

, 2013
Carbonate stripping by treatment of SVs with 100 mM sodium carbonate was used to determine if Mover is integrally or peripherally associated with SV membranes.
Thomas Dresbach (19614), Jan Hoeber (415718), Asha Kiran Akula (415719), Thomas Kremer (412552), Henning Urlaub (22208), Saheeb Ahmed (415717), Nina Wittenmayer (328227), Camin Dean (408092), Markus Islinger (107131), Joachim Kirsch (50842)   +9 more
core   +1 more source

Serum proteomic biomarker investigation of vascular depression using data-independent acquisition: a pilot study

Frontiers in Aging Neuroscience
BackgroundVascular depression (VaD) is a depressive disorder closely associated with cerebrovascular disease and vascular risk factors. It remains underestimated owing to challenging diagnostics and limited information regarding the pathophysiological ...
Liuyi Lan, Sisi Peng, Ran Zhang, Haoying He, Yong Yang, Bing Xi, Junjian Zhang   +6 more
doaj   +1 more source

ATP‐Mediated Bidirectional Communication Between Natural and Artificial Cells for Controlled Bioreactions

Advanced Functional Materials, EarlyView.
Establishment of bidirectional communication behavior between natural and artificial cells. The first type of communication from natural dendritic cells to artificial polymeric cells was achieved via ATP release after cell lysis. The released ATP was taken up via gated UV‐controlled permeability increase of the polymeric membrane for performing ...
Ilona Kalte, Tsvetomir Ivanov, Leonhard Seufert, Shoupeng Cao, Lucas Caire da Silva, Volker Mailänder, Katharina Landfester   +6 more
wiley   +1 more source

Role of Vesicle-associated Membrane Protein 2 in Glucagon-like Peptide-1 Secretion [PDF]

, 2013
Glucagon-like peptide-1 (GLP-1) is an incretin hormone produced by the enteroendocrine L-cell that potently stimulates insulin secretion. Although signaling pathways promoting GLP-1 secretion are well characterized, the mechanism by which GLP-1 ...
Li, Samantha
core   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

GPS2 is required for the association of NS5A with VAP-A and hepatitis C virus replication.

PLoS ONE, 2013
Hepatitis C virus (HCV) nonstructural protein 5A (NS5A) is a component of the replication complex associated with various cellular proteins. It has been reported that G protein pathway suppressor 2 (GPS2) is a potential NS5A-binding factor, as identified
Guodong Xu, Xiu Xin, Congyi Zheng
doaj   +1 more source

Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms

Advanced Functional Materials, EarlyView.
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger, Min Jiang, Florian Belger, Fabian Link, Benjamin Winkeljann, Olivia M. Merkel   +5 more
wiley   +1 more source