Results 131 to 140 of about 498,271 (378)

Programmed Fabrication of Vesicle‐Based Prototissue Fibers with Modular Functionalities

Advanced Science
Multicellular organisms have hierarchical structures where multiple cells collectively form tissues with complex 3D architectures and exhibit higher‐order functions.
Tomoya Kojima, Kouichi Asakura, Pierangelo Gobbo, Taisuke Banno   +3 more
doaj   +1 more source

On the surface tension of fluctuating quasi-spherical vesicles [PDF]

arXiv, 2010
We calculate the stress tensor for a quasi-spherical vesicle and we thermally average it in order to obtain the actual, mechanical, surface tension $\tau$ of the vesicle. Both closed and poked vesicles are considered. We recover our results for $\tau$ by differentiating the free-energy with respect to the proper projected area.
arxiv  

Flocculation of vesicles

, 2011
The flocculation of liposomes is theoretically studied. An expression for the flocculation activation energy is derived, accounting for the electrostatic and hydrophobic interactions as well as for the correlation area of floc-spots.
openaire   +2 more sources

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

Unraveling How Antimicrobial Lipid Mixtures Disrupt Virus-Mimicking Lipid Vesicles: A QCM-D Study

Biomimetics
Single-chain lipid amphiphiles such as fatty acids and monoglycerides are promising antimicrobial alternatives to replace industrial surfactants for membrane-enveloped pathogen inhibition.
Suji Moon, Tun Naw Sut, Bo Kyeong Yoon, Joshua A. Jackman   +3 more
doaj   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

Lipid-Based Catalysis Demonstrated by Bilayer-Enabled Ester Hydrolysis

Membranes
Lipids have not traditionally been considered likely candidates for catalyzing reactions in biological systems. However, there is significant evidence that aggregates of amphiphilic compounds are capable of catalyzing reactions in synthetic organic ...
Shu Liu, Kiran Kumar, Tracey Bell, Ayyalusamy Ramamoorthy, David Van Winkle, Steven Lenhert   +5 more
doaj   +1 more source

Stokesian jellyfish: Viscous locomotion of bilayer vesicles

, 2010
Motivated by recent advances in vesicle engineering, we consider theoretically the locomotion of shape-changing bilayer vesicles at low Reynolds number.
Antonietti, Antunes, Arthur A. Evans, Becker, Bottino, Breidenich, Brennen, Brochard, Campelo, Childress, Dreyfus, Eric Lauga, Fu, Goldman, Golestanian, Grimm, Guo, Howse, Huang, Jeffery, Jiang, Kukula, Kulic, Käs, Lauga, Lauga, Leoni, Leshansky, Leshansky, Li, Lipowsky, McMahon, Najafi, Nikolov, Petrov, Power, Purcell, Ramaswamy, Reigada, Saad, Saverio E. Spagnolie, Seifert, Seifert, Spagnolie, Spagnolie, Stone, Veksler, Wang, Yang, Yu   +49 more
core   +1 more source

Interplay of integrins and selectins in metastasis

Molecular Oncology, EarlyView.
Here we review the role of integrins and their interplay with selectins in metastasis. The efficacy of integrin‐targeted therapies may be reduced in tumors where metastasis relies heavily on selectins. In certain tumors, integrins and selectins exhibit a synergistic interaction during intraperitoneal dissemination.
Diana Maltseva, Ashot Nersisyan, Alexander Tonevitsky   +2 more
wiley   +1 more source

Fabrication of Porous Collagen Scaffolds Containing Embedded Channels with Collagen Membrane Linings

Micromachines
Tissues and organs contain an extracellular matrix (ECM). In the case of blood vessels, endothelium cells are anchored to a specialized basement membrane (BM) embedded inside the interstitial matrix (IM).
Neda Fakhri, Arezoo Khalili, Terry Sachlos, Pouya Rezai   +3 more
doaj   +1 more source