Results 161 to 170 of about 516,191 (353)

Polyoxyethylene Group-Dependent Surface Properties and Aggregation Behavior in Oleyl-Based Sulfosuccinate Systems

open access: yesMolecules
Three oleyl-based sulfosuccinates with different polyoxyethylene (EO) chain length (MS-OEn, where n = 3, 5, 7) were synthesized, and their structure were confirmed using FT-IR and ¹H NMR analyses.
Ping Li   +5 more
doaj   +1 more source

Cognitive Resilience in Apolipoprotein ε4 Carrier Women Predicted by Neuron‐Derived Extracellular Vesicles

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos   +17 more
wiley   +1 more source

Peptide based vesicles for cancer immunotherapy: design, construction and applications

open access: yesFrontiers in Immunology
Cancer immunotherapy has emerged as a powerful strategy for clinical treatment of malignant cancers. Despite the advances, cancer immunotherapy has met several challenges such as the limited efficacy to small subsets of patients, and serious autoimmune ...
Yulin Yu   +7 more
doaj   +1 more source

Repeat Expansions in PLIN4 Cause Autosomal Dominant Vacuolar Myopathy With Sarcolemmal Features

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We aim to describe and characterize two unrelated Spanish families suffering from an autosomal dominant autophagic vacuolar myopathy caused by repeat expansions in PLIN4. Methods We evaluated the clinical phenotype and muscle imaging, and performed a genetic workup that included exome sequencing, muscle RNAseq, and long‐read genome ...
Laura Llansó   +17 more
wiley   +1 more source

Epidermal lamellar bodies, essential organelles for the skin barrier

open access: yesFrontiers in Cell and Developmental Biology
Skin lamellar bodies are members of the Lysosome-Related-Organelle (LRO) family, characterized by specific features related to the skin’s primary function, i.e., protecting the body from external assaults while minimizing dehydration.
Corinne Leprince, Michel Simon
doaj   +1 more source

Risk of Hepatotoxicity in Patients With Gout Treated With Febuxostat or Benzbromarone: A Propensity Score–Matched Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective The objective of this study was to evaluate and compare the risk of hepatotoxicity associated with the use of febuxostat and benzbromarone in patients with gout. Methods New users of febuxostat or benzbromarone with monitoring of liver function at least three times in a year after initiation of the study drugs were identified from an ...
Wenyan Sun   +8 more
wiley   +1 more source

Vesicle-Substrate Interaction [PDF]

open access: yes, 1992
Kremer, K.   +4 more
core   +1 more source

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