Results 51 to 60 of about 498,271 (378)

Kinetic Pathway and Micromechanics of Vesicle Fusion/Fission [PDF]

open access: yesarXiv, 2023
Despite the wide existence of vesicles in living cells as well as their important applications like drug-delivery, the underlying mechanism of vesicle fusion/fission remains under debate. Here, we develop a constrained self-consistent field theory (SCFT) which allows tracking the shape evolution and free energy as a function of center-of-mass ...
arxiv  

Cross-stream migration of a vesicle in vortical flows [PDF]

open access: yes, 2022
We use numerical simulations to systematically investigate the vesicle dynamics in two-dimensional (2D) Taylor-Green vortex flow in the absence of inertial forces. Vesicles are highly deformable membranes encapsulating an incompressible fluid and they serve as numerical and experimental proxies for biological cells such as red blood cells.
arxiv   +1 more source

Dynamics of Vesicle Formation from Lipid Droplet: Mechanism and Controllability

open access: yes, 2009
A coarse-grained model developed by Marrink et al. [J. Phys. Chem. B 111, 7812 (2007)] is applied to investigate vesiculation of lipid [dipalmitoylphosphatidylcholine (DPPC)] droplets in water.
Helfrich W., Xuehao He, Zilu Wang
core   +1 more source

Macrophage Cell Membrane Coating on Piperine-Loaded MIL-100(Fe) Nanoparticles for Breast Cancer Treatment

open access: yesJournal of Functional Biomaterials, 2023
Piperine (PIP), a compound found in Piper longum, has shown promise as a potential chemotherapeutic agent for breast cancer. However, its inherent toxicity has limited its application. To overcome this challenge, researchers have developed PIP@MIL-100(Fe)
Christian Rafael Quijia   +7 more
doaj   +1 more source

Circulatory microRNAs in helminthiases: Potent as diagnostics biomarker, its potential role and limitations

open access: yesFrontiers in Veterinary Science, 2022
Infections caused by helminths are responsible for severe public health problems and economic burden on continental scale. Well-timed and precise diagnosis of helminth infections is critical for taking by appropriate approaches for pathogen control ...
Hanif Ullah   +10 more
doaj   +1 more source

Characteristic spatial scale of vesicle pair interactions in a plane linear flow

open access: yes, 2012
We report the experimental studies on interaction of two vesicles trapped in a microfluidic analog of four-roll mill, where a plane linear flow is realized.
Eldad Afik   +4 more
core   +3 more sources

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Preparation of Liposomes from Soy Lecithin Using Liquefied Dimethyl Ether

open access: yesFoods, 2021
We investigated a method to prepare liposomes; soy lecithin was dissolved in liquefied dimethyl ether (DME) at 0.56 MPa, which was then injected into warm water. Liposomes can be successfully prepared at warm water temperatures above 45 °C.
Hideki Kanda   +3 more
doaj   +1 more source

A transient solution for vesicle electrodeformation and relaxation

open access: yes, 2012
A transient analysis for vesicle deformation under DC electric fields is developed. The theory extends from a droplet model, with the additional consideration of a lipid membrane separating two fluids of arbitrary properties.
Lin, Hao   +3 more
core   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

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