Results 161 to 170 of about 1,068,905 (341)

Dynamical description of vesicle growth and shape change

open access: yes, 2010
We systematize and extend the description of vesicle growth and shape change using linear nonequilibrium thermodynamics. By restricting the study to shape changes from spheres to axisymmetric ellipsoids, we are able to give a consistent formulation which
Alan J. McKane   +8 more
core   +1 more source

Adipose Mesenchymal Stem Cell‐Derived Exosomes in Conjunction with Roflumilast Ameliorate Chronic Kidney Disease Through the Modulation of Fibrosis and Inflammation

open access: yesAdvanced Biology, EarlyView.
The novelty of this study showed that the injection of exosomes produced from ADMSCs in combination with Roflumilast poses a more favorable therapeutic outcome for CKD induced by Adriamycin, compared to therapy with exosomes or Roflumilast alone. Roflumilast and exosomes treatment lowered the expression of the apoptotic, fibrotic, and inflammatory ...
Mohamed Ali   +5 more
wiley   +1 more source

Shedding light on the cell biology of extracellular vesicles

open access: yesNature reviews. Molecular cell biology, 2018
G. Niel, G. D’angelo, G. Raposo
semanticscholar   +1 more source

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

open access: yesAdvanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna   +6 more
wiley   +1 more source

Editorial: Exploring the mechanical properties of soft materials at multiple length scales

open access: yesFrontiers in Physics, 2022
Marco Laurati   +4 more
doaj   +1 more source

A Spatially Resolved View on the Aging Substantia nigra: An Exploratory Proteomic Study

open access: yesAdvanced Biology, EarlyView.
Although aging is the most important risk factor for several neurodegenerative diseases, the molecular effects of physiological aging are still understudied. By applying spatially‐resolved proteomic analyses of the human substantia nigra pars compacta, alterations in vesicular trafficking and mitochondrial proteins are observed, as well as reduced ...
Britta Eggers   +10 more
wiley   +1 more source

Thermally Induced Gelling Systems Based on Patchy Polymeric Micelles

open access: yesAdvanced Functional Materials, Volume 35, Issue 12, March 18, 2025.
A novel strategy to design thermally induced gelling systems with tunable material properties is reported. Polymeric mixed‐shell micelles displaying multiple thermosensitive patchy domains formed hydrogels by assembling into well‐entangled worm‐like network structures upon heating to body temperature. The patchy micelle design significantly affects the
Binru Han   +9 more
wiley   +1 more source

Evolving Platinum‐Copper Nanostructures for Enhanced Photothermal Therapy and Controlled Copper Release in Cancer Therapy

open access: yesAdvanced Functional Materials, EarlyView.
Platinum‐Copper bimetallic nanoparticles may evolve depending on their synthesis under tumor microenvironment conditions and play a dual role as chemotherapeutic agents after releasing Cu ions and as near infrared photothermal agents with the Pt‐rich remaining frames.
Jose I. Garcia‐Peiro   +7 more
wiley   +1 more source

Extracellular vesicle biomarkers for cognitive impairment in Parkinson’s disease [PDF]

open access: bronze, 2022
Joseph Blommer   +11 more
openalex   +1 more source

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