Results 141 to 150 of about 80,112 (305)

Lysosomal Delivery of Bioactive Proteins to Living Human Cells via Engineered Exosomes [PDF]

open access: yes, 2018
Exosomes are naturally secreted nanovesicles derived from mammalian cells that are used for intercellular communication in vivo. As a result, they can potentially be used for intracellular delivery of therapeutics for disease treatment. We have developed
Levy, Daniel
core   +1 more source

Variation in RNA Virus Mutation Rates across Host Cells [PDF]

open access: yes, 2014
It is well established that RNA viruses exhibit higher rates of spontaneous mutation than DNA viruses and microorganisms. However, their mutation rates vary amply, from 10−6 to 10−4 substitutions per nucleotide per round of copying (s/n/r) and the causes
A Carreau   +69 more
core   +4 more sources

Protocol for constructing and characterizing recombinant vectored vaccines for rabies virus

open access: yesSTAR Protocols
Summary: Recombinant vectored vaccines provide economical, rapidly engineered, and tailored immunization strategies. Here, we present a protocol for constructing and characterizing recombinant vectored vaccines for rabies virus (RV).
Manar E. Khalifa, Muhammad Munir
doaj  

Cellular microRNAs Repress Vesicular Stomatitis Virus but Not Theiler’s Virus Replication

open access: yesViruses, 2016
Picornavirus’ genomic RNA is a positive-stranded RNA sequence that also serves as a template for translation and replication. Cellular microRNAs were reported to interfere to different extents with the replication of specific picornaviruses, mostly ...
Aurélie De Cock, Thomas Michiels
doaj   +1 more source

Structure of the Vesicular Stomatitis Virus N0-P Complex

open access: yesPLoS Pathogens, 2011
Replication of non-segmented negative-strand RNA viruses requires the continuous supply of the nucleoprotein (N) in the form of a complex with the phosphoprotein (P).
C. Leyrat   +7 more
semanticscholar   +1 more source

From Bat to Worse: The Pivotal Role of Bats for Viral Zoonosis

open access: yesMicrobial Biotechnology, Volume 18, Issue 7, July 2025.
Thanks to a dampened inflammatory innate immune response, various Chiropteran (bat) species frequently carry ‐ without showing symptoms – diverse viruses that can cause severe diseases in humans. The reasons why bats are a pivotal virus reservoir for emerging viral diseases are discussed in this Lilliput contribution.
Harald Brüssow
wiley   +1 more source

Tumor Necrosis Factor-mediated survival of CD169+ cells promotes immune activation during vesicular stomatitis virus infection [PDF]

open access: yes, 2017
Innate immune activation is essential to mount an effective antiviral response and to prime adaptive immunity. Although a crucial role of CD169+ cells during vesicular stomatitis virus (VSV) infections is increasingly recognized, factors regulating CD169+
Bellora, Nicolas   +28 more
core   +8 more sources

SENSITIVITY OF TRANSGENIC CHICORY PLANTS WITH HUMAN INTERFERON ALPHA-2B GENE TO DAMAGE BY TOBACCO MOSAIC VIRUS

open access: yesMìkrobìologìâ ì Bìotehnologìâ, 2011
The sensitivity to tobacco mosaic virus of transgenic chicory Cichorium intybus L. with interferon-α2b gene was compared with non-transformed chicory plants.
Н. А. Матвєєва   +4 more
doaj   +1 more source

p53 Deficiency in Colon Cancer Cells Promotes Tumor Progression Through the Modulation of Meflin in Fibroblasts

open access: yesCancer Science, Volume 116, Issue 7, Page 1871-1882, July 2025.
TP53 deficiency in colon cancer cells suppresses Meflin expression in fibroblasts and promotes fibroblast‐mediated tumor growth. Suppression of Meflin expression could transform normal fibroblasts into ones exhibiting a CAF‐like phenotype, promoting colon cancer cell growth.
Eiji Kimura   +17 more
wiley   +1 more source

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