Results 241 to 250 of about 65,214 (257)
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The fine structure of vesicular stomatitis virus
Virology, 1968Abstract The structure of bullet-shaped (B) and truncated (T) particles of vesicular stomatitis virus was examined by electron microscopy using negative staining and thin sectioning techniques. The conformation of the internal, probably nucleoprotein, component in intact and disintegrating particles was investigated, and the following conclusions ...
A.F. Howatson +3 more
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The development and structure of vesicular stomatitis virus
Virology, 1962Abstract Thin sections of L cells infected with vesicular stomatitis virus were examined by electron microscopy. Fingerlike projections at the cell surfaces were identified as virus particles in the process of formation. Concentrates of virus particles were examined by the thin section and by the negative contrast method, and details of their ...
A.F. Howatson +3 more
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Structural components of vesicular stomatitis virus
Virology, 1966Abstract Fixed and unfixed suspensions of vesicular stomatitis virus (VSV) were examined by negative contrast techniques. The internal component of this virus showed two modes of release: (1) It was found free of the viral envelope as a large helical cylinder (500–550 A × 1600–2000 A) in various stages of disorganization.
Rolf E. Hauser, Robert W. Simpson
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Vesicular Stomatitis Virus as an Oncolytic Vector
Viral Immunology, 2004Recent data has shown that viruses such as vesicular stomatitis virus (VSV), a relatively non-pathogenic, negative-stranded RNA virus, can preferentially replicate in malignant cells and less so in normal cells. VSV appears able to carry out this function in transformed cells since these hosts exhibit the hallmarks of flawed host defense, probably ...
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Vesicular stomatitis virus: re-inventing the bullet
Trends in Molecular Medicine, 2004As our understanding of the molecular aspects of human disease increases, it is becoming possible to create designer therapeutics that are exquisitely targeted and have greater efficacy and fewer side effects. One class of targeted biological agents that has benefited from recent advances in molecular biology is designer viruses.
Lichty, B. +3 more
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Susceptibility of Zebrafish to Vesicular Stomatitis Virus Infection
Zebrafish, 2018The zebrafish, Danio rerio, has become recognized as a valuable model for infectious diseases. Here we evaluated the susceptibility of zebrafish to be infected with the mammalian vesicular stomatitis virus (VSV). Both zebrafish cells and embryos were highly susceptible to VSV infection.
Sabela Da Silva-Álvarez +7 more
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Vesicular Stomatitis Virus Pseudotypes of Retroviruses
2003Pseudotype viruses are phenotypically mixed virions containing the genome or nucleocapsid of one enveloped virus and the surface or envelope (env) glycoproteins of another. This chapter will concentrate on vesicular stomatitis virus (VSV) pseudotypes retaining the VSV nucleocapsid but with alternative env glycoproteins derived from retroviruses.
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Transcription of Vesicular Stomatitis Virus
1987Up until 1970, it was not understood why the deproteinized genomic RNAs of positive-strand viruses such as poliovirus were infectious while those of negative-strand viruses such as vesicular stomatitis virus (VSV) were not. An explanation of this difference was obtained when Baltimore et al. (1970) incubated highly purified virions of VSV with nonionic
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