The Cryo-EM Structure of Vesivirus 2117 Highlights Functional Variations in Entry Pathways for Viruses in Different Clades of the Vesivirus Genus [PDF]
Abstract Vesivirus 2117 is an adventitious agent that has been responsible for lost productivity in biopharmaceutical production following contamination of Chinese hamster ovary cell cultures in commercial bioreactors.
James Streetley +2 more
exaly +6 more sources
Vesivirus 2117 capsids more closely resemble sapovirus and lagovirus particles than other known vesivirus structures [PDF]
Vesivirus 2117 is an adventitious agent that, in 2009, was identified as a contaminant of Chinese hamster ovary cells propagated in bioreactors at a pharmaceutical manufacturing plant belonging to Genzyme. The consequent interruption in supply of Fabrazyme and Cerezyme (drugs used to treat Fabry and Gaucher diseases, respectively) caused significant ...
Grant Hansman +2 more
exaly +6 more sources
Characterization of a Vesivirus Associated with an Outbreak of Acute Hemorrhagic Gastroenteritis in Domestic Dogs [PDF]
ABSTRACTFour of eleven affected dogs died despite aggressive treatment during a 2015 focal outbreak of hemorrhagic gastroenteritis following a stay in a pet housing facility. Routine diagnostic investigations failed to identify a specific cause. Virus isolation from fresh necropsy tissues yielded a calicivirus with sequence homology to a vesivirus ...
Randall Renshaw, Edward Dubovi
exaly +4 more sources
Isolation and characterization of a new Vesivirus from rabbits [PDF]
This report describes the isolation, cDNA cloning, complete genome nucleotide sequence, and partial characterization of a new cultivable calicivirus isolated from juvenile feeder European rabbits (Oryctolagus cuniculus) showing symptoms of diarrhea. Absence of neutralization by type-specific neutralizing antibodies for 40 caliciviruses and phylogenetic
Francisco Parra +2 more
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Vesivirus viremia and seroprevalence in humans [PDF]
Pathogenic caliciviruses of the genus Vesivirus circulate in oceanic ecosystems and spread to and among terrestrial mammals. Isolation of Vesivirus from natural and laboratory infections in humans led to this investigation of Vesivirus seroprevalence and viremia.
Patrick Iversen
exaly +3 more sources
Related searches:
Caliciviridae and Vesivirus 2117
BioProcessing: Advances and Trends in Biological Product Development, 2011Yongchang Qiu
exaly +2 more sources
Feline caliciviruses (FCVs) have occasionally been described in cats in association with enteric disease, but an etiological role for these viruses in acute gastroenteritis is still unclear. In this study, molecular characterization of FCV and feline norovirus (FNoV) was undertaken using real-time PCR (RT-PCR) and sequence analysis of the ORF1 region ...
Tulio Fumian +2 more
exaly +3 more sources
Serologic evidence of vesivirus-specific antibodies associated with abortion in horses
Journal of the American Veterinary Medical Association, 2006Abstract Objective —To test horses for serologic evidence of an association between vesiviral antibodies and abortion. Sample Population —Sera from 141 horses.
Andreas, Kurth +2 more
openaire +3 more sources
Inhibition of Vesivirus Infections in Mammalian Tissue Culture with Antisense Morpholino Oligomers
Oligonucleotides, 2001Caliciviruses infect and cause disease in animals and humans. They are nonenveloped, positive-stranded RNA viruses with a genome of approximately 7.5 kb that encodes viral proteins in three open reading frames (ORF). Antisense oligomers targeting one of the three ORF of caliciviruses of the genus Vesivirus significantly inhibit viral replication in ...
Patrick Iversen +2 more
exaly +3 more sources

