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Viroporins: emerging viral infection mechanisms and therapeutic targets [PDF]
Journal of VirologyViroporins, virus-encoded small hydrophobic proteins, are involved in critical steps of viral infections by modulating ion homeostasis, disrupting host membrane integrity, and orchestrating key stages of the virus life cycle—from entry and replication to
Yuxin Qu +8 more
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Vpu Protein: The Viroporin Encoded by HIV-1 [PDF]
Viruses, 2015 Viral protein U (Vpu) is a lentiviral viroporin encoded by human immunodeficiency virus type 1 (HIV-1) and some simian immunodeficiency virus (SIV) strains.
Maria Eugenia Gonzalez
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Antiviral effect of the viroporin inhibitors against Taiwan isolates of infectious bronchitis virus (IBV) [PDF]
Virus ResearchCoronaviruses (CoVs) are significant animal and human pathogens, characterized by being enveloped RNA viruses with positive-sense single-stranded RNA. The Coronaviridae family encompasses four genera, among which gammacoronaviruses pose a major threat to
Hung-Jen Liu, Chi-Young Wang
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Membrane Activity and Viroporin Assembly for the SARS-CoV-2 E Protein Are Regulated by Cholesterol [PDF]
BiomoleculesThe SARS-CoV-2 E protein is an enigmatic viral structural protein with reported viroporin activity associated with the acute respiratory symptoms of COVID-19, as well as the ability to deform cell membranes for viral budding.
Marta V Volovik +2 more
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Poultry Science, 2021 : Duck hepatitis A virus 1 (DHAV-1) can cause high morbidity and fatal acute infectious hepatitis in ducklings, which seriously endangers animal husbandry. Viroporin is a small molecular weight hydrophobic transmembrane protein encoded by the virus, that
Anchun Cheng, Xumin Ou, Sai Mao
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Vaccines, 2022 To improve the production of foot-and-mouth disease (FMD) molecular vaccines, we sought to understand the effects of the FMD virus (FMDV) 2B viroporin in an experimental, plasmid-based, virus-like particle (VLP) vaccine.
Victoria Primavera +2 more
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The 6-kilodalton peptide 1 of the family Potyviridae: small in size but powerful in function [PDF]
Frontiers in MicrobiologyThe Potyviridae family is one of the most economically significant groups of plant RNA viruses, causing severe yield losses in agriculturally important crops.
Liansheng Yu +7 more
doaj +2 more sources
MSphere, 2019 Enteric viruses in the Caliciviridae family cause acute gastroenteritis in humans and animals, but the cellular processes needed for virus replication and disease remain unknown.
Jacob L Perry +2 more
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Viruses, 2022 The leader of the capsid (LC) protein is exclusive to the Vesivirus genus, and it is needed for successful feline calicivirus (FCV) replication, as well as an efficient apoptosis induction through the mitochondrial pathway.
Lizbeth Salazar-Villatoro +1 more
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In Support of Simian Polyomavirus 40 VP4 as a Later Expressed Viroporin
MSphere, 2020 Simian virus 40 VP4 was discovered in 2007 as a later expressed viral protein initiated from a downstream Met on the VP2/VP3 transcript. VP4’s role as a viroporin involved in viral release was supported in a series of additional articles that ...
Robert Daniels, Daniel N Hebert
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