Results 11 to 20 of about 3,761 (176)
Vpu Protein: The Viroporin Encoded by HIV-1 [PDF]
Viruses, 2015 Viral protein U (Vpu) is a lentiviral viroporin encoded by human immunodeficiency virus type 1 (HIV-1) and some simian immunodeficiency virus (SIV) strains.
Maria Eugenia Gonzalez
exaly +8 more sources
Vaccines, 2022 To improve the production of foot-and-mouth disease (FMD) molecular vaccines, we sought to understand the effects of the FMD virus (FMDV) 2B viroporin in an experimental, plasmid-based, virus-like particle (VLP) vaccine.
Michael Puckette +2 more
exaly +4 more sources
Viroporins: emerging viral infection mechanisms and therapeutic targets [PDF]
Journal of VirologyViroporins, virus-encoded small hydrophobic proteins, are involved in critical steps of viral infections by modulating ion homeostasis, disrupting host membrane integrity, and orchestrating key stages of the virus life cycle—from entry and replication to
Yuxin Qu +8 more
doaj +4 more sources
A hidden gene in astroviruses encodes a viroporin [PDF]
Nature Communications, 2020 Astroviruses are common human pathogens and their genomes contain three known protein-coding genes. Here, Lulla et al. report a fourth, previously overlooked gene encoding protein XP which has a viroporin-like activity that is important for efficient ...
Valeria Lulla, Andrew E. Firth
doaj +19 more sources
Antiviral Effect of the Viroporin Inhibitors Against Taiwan Isolates of Infectious Bronchitis Virus (IBV) [PDF]
Virus ResearchCoronaviruses (CoVs) are significant animal and human pathogens, characterized by being enveloped RNA viruses with positive-sense single-stranded RNA. The Coronaviridae family encompasses four genera, among which gammacoronaviruses pose a major threat to
Chi-Young Wang +2 more
exaly +4 more sources
Comparative Genomics of Viral Genomes and Identification of Three Novel Viroporin-Like Superfamilies [PDF]
Microbial PhysiologyIntroduction: Viroporins are small multifunctional proteins that modify cellular membranes facilitating processes such as viral nucleic acid entry and the release of virions from infected cells.
Jianing Wang +6 more
doaj +2 more sources
Ebola Virus Delta Peptide Is a Viroporin [PDF]
Journal of Virology, 2017 The Ebola virus (EBOV) genome encodes a partly conserved 40-residue nonstructural polypeptide, called the delta peptide, that is produced in abundance during Ebola virus disease (EVD).
Peter C. Searson +11 more
core +3 more sources
The SH protein of mumps virus is a druggable pentameric viroporin. [PDF]
Sci AdvViral infections are on the rise and drugs targeting viral proteins are needed. Viroporins constitute a growing groupof virus-encoded transmembrane oligomeric proteins that allow passage of small molecules across the membrane.Despite sparsity in ...
Devantier K +15 more
europepmc +8 more sources
Does the Evidence Support the Existence of the Simian Polyomavirus SV40 Vp4 Viroporin? [PDF]
mSphere, 2020 The simian polyomavirus SV40 was reported to express Vp4, an N-terminally truncated form of the minor capsid proteins Vp2 and Vp3. Since a missense mutation of the putative Vp4 start codon (Vp2M228I) was found to give reduced progeny release and delayed ...
Stian Henriksen +1 more
doaj +2 more sources
Poultry Science, 2021 : Duck hepatitis A virus 1 (DHAV-1) can cause high morbidity and fatal acute infectious hepatitis in ducklings, which seriously endangers animal husbandry. Viroporin is a small molecular weight hydrophobic transmembrane protein encoded by the virus, that
Sai Mao, Anchun Cheng, Juan Huang
exaly +3 more sources