Results 91 to 100 of about 589,793 (294)

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Comparison of retinal microvasculature in anisometropic amblyopic and healthy eyes using optical coherence tomography angiography

Indian Journal of Ophthalmology
Purpose: To compare the optical coherence tomography angiography (OCTA) findings of retinal microvasculature in anisometropic amblyopic eyes with fellow eyes.
Tisha Thomas Menacherry, V Rajesh Prabu, Jagadeesh Kumar Reddy, Suruthi Nagarajan, Mithun Thulasidas   +4 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Confocal Microscopy Study of Neurovascular Distribution in Facial Port Wine Stains (Capillary Malformation)

Journal of the Formosan Medical Association, 2008
Background/Purpose: Vascular ectasia observed in port wine stain (PWS) birthmarks might be secondary to localized reduction of neural innervation and associated loss of autonomic stimulation.
Cheng-Jen Chang, Jau-Song Yu, J. Stuart Nelson   +2 more
doaj   +1 more source

Autoimmune retinopathy: findings and limitations from optical coherence tomography angiography

International Journal of Retina and Vitreous, 2020
Background and objective To report novel findings and limitations from optical coherence tomography angiography (OCTA) in the evaluation of autoimmune retinopathy (AIR).
Joseph Raevis, Tyler Etheridge, Spencer Cleland, Mihai Mititelu   +3 more
doaj   +1 more source

The relationship between oestrogen receptor-alpha phosphorylation and the tumour microenvironment in patients with primary operable ductal breast cancer [PDF]

, 2017
Aims: Although the role of phosphorylation of oestrogen receptor (ER) at serines 118 (p-S118) and 167 (p-S167) has been studied, the relationship between p-S118, p-S167 and the tumour microenvironment in ER-positive primary operable ductal breast ...
Arnold, Bartlett, Brouckaert, Ciucci, Fan, Faratian, Gilchrist, Gujam, Gujam, Harvey, Jiang, Kirkegaard, Klintrup, Kok, Lannigan, Li, McCarty, Medrek, Mohammed, Mohammed, Mohammed, Mohammed, Mohammed, Mohammed, Mouridsen, Paik, Ring, Roxburgh, Salhia, Sarwar, Srinivas, Svensson, Toy, Ueno, Uzzan, Vassilakopoulou, Weitsman, Yamashita, Yamashita   +38 more
core   +1 more source

Aquaporin‐4 in Narcolepsy Type 1: Investigation of Perivascular Fluid Movement in Sleep Disorders

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Narcolepsy type 1 (NT1) is caused by the loss of hypocretin‐1 leading to excessive daytime sleepiness and cataplexy. Additionally, disrupted nighttime sleep has become an increasingly recognized feature of NT1. As the glymphatic fluid movement has been linked to sleep architecture, we investigated cerebrospinal fluid (CSF) Aquaporin‐4 (AQP4 ...
Jonas Ranke, Petra Steinacker, Steffen Halbgebauer, Patrick Oeckl, Geert Mayer, Markus Otto   +5 more
wiley   +1 more source

Anti‐CD19 CAR T Cells in Autoimmune Encephalitis: Inflammation Controlled, Neurodegeneration Unchecked?

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Just recently, successful chimeric antigen receptor (CAR) T cell therapy was reported in the first patient with refractory, anti‐diacylglycerol lipase alpha (DAGLA) antibody‐mediated autoimmune encephalitis, achieving partial clinical remission.
Dimitrios Mougiakakos, Marwa Al‐Dubai, Denise Walther, Dominic Borie, Jan D. Lünemann, Marc Pawlitzki, Sven G. Meuth, Solveig Henneicke, Stefan Vielhaber, Stefanie Schreiber   +9 more
wiley   +1 more source

Peripapillary vessel density in eyes with cone-rod dystrophy

PLOS ONE
Purpose To compared the vessel density (VD) around the optic nerve head (ONH) in eyes with cone-rod dystrophy (CORD) and healthy control eyes in a sector-wise manner and to investigate the relationship between VD around the ONH and visual function in CORD eyes.
Masato Shinozuka, Mizuho Arai, Yumeno Hirayama, Yuna Uechi, Shohei Kawasaki, Kazuyoshi Okawa, Yume Iwashita, Misa Miyazato, Kazushi Hirono, Kentaro Nakamura, Tatsuya Inoue, Ryo Asaoka, Yasuo Yanagi, Maiko Maruyama-Inoue, Kazuaki Kadonosono   +14 more
openaire   +3 more sources

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source