Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu +9 more
wiley +1 more source
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo +14 more
wiley +1 more source
A combination of MRI diffusion-derived vessel density (DDVD) and slow diffusion coefficient (SDC) can reliably diagnose liver hemangioma: a testing of three centers' data. [PDF]
Hu GW +9 more
europepmc +1 more source
ABSTRACT Genome‐wide association studies (GWAS) link the Tropomyosin 1 (Tpm1) locus to quantitative blood trait variation, but related mechanisms are unclear. Tpm1 encodes an actin‐binding protein that regulates actin filament diversity, cell adhesion, signaling, and actomyosin contractility.
Po‐Lun Kung +19 more
wiley +1 more source
[The influence of microvessel density and microlymphatic vessel density on prognosis in hypopharyngeal carcinoma and the construction]. [PDF]
Xu C +6 more
europepmc +1 more source
Relationship Between Intracranial Pressure, Ocular Blood Flow and Vessel Density: Insights from OCTA and Doppler Imaging. [PDF]
Zizas A +7 more
europepmc +1 more source
Entorhinal vessel density correlates with phosphorylated tau and TDP-43 pathology. [PDF]
Llamas Rodríguez J +8 more
europepmc +1 more source
Separation of liver focal nodular hyperplasia (FNH) and liver malignant tumors by a combination of T2-weighted imaging signal and three diffusion magnetic resonance metrics of diffusion-derived vessel density, slow diffusion coefficient, and apparent diffusion coefficient. [PDF]
Li CY +4 more
europepmc +1 more source
Exploring retinal vessel density alterations in prolactinoma patients: Insights from OCTA imaging. [PDF]
Hayat SC +3 more
europepmc +1 more source

