Results 141 to 150 of about 34,204 (315)

Molecular basis for a pore block of Tentonin 3 expressed in HEK293 cells by a conopeptide, NMB‐1

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Tentonin 3 (TTN3/TMEM150C) is a mechanosensitive ion channel that plays critical roles in mechanotransduction processes. TTN3 forms a tetramer with a predicted rectangular shape and a central pore. A conotoxin ρ‐TIA and its synthetic analog, noxious mechanosensation blocker 1 (NMB‐1), were initially developed to inhibit slowly ...
Sujin Lim   +10 more
wiley   +1 more source

Role of hydrops MRI in differentiating between Menière’s disease and vestibular migraine: a prospective study [PDF]

open access: gold
Anja Bernaerts   +8 more
openalex   +1 more source

Biallelic RFC1 Expansions Are a Rare Cause of Early‐Onset and Familial Parkinson's Disease

open access: yesClinical Genetics, EarlyView.
Biallelic pathogenic expansions in RFC1 contribute to the genetic etiology of PD, with a frequency similar to that of other known autosomal recessive PD genes. RFC1‐positive PD is currently not clinically distinguishable from RFC1‐negative PD, but genetic background may play a role in future therapies or other interventions.
Anja Kovanda   +11 more
wiley   +1 more source

Long‐Term Clinical, Radiographic and Esthetic Outcomes of Zirconia Dental Implants: A 10‐Year Prospective Multicenter Study

open access: yesClinical Oral Implants Research, EarlyView.
ABSTRACT Objectives This study aimed to prospectively investigate the long‐term clinical performance of a commercially available one‐piece zirconia dental implant system over 10 years. Material and Methods A multicenter, open‐label study was conducted at three clinical centers in Germany.
S. Roehling   +5 more
wiley   +1 more source

Acute neurologic presentation of a 2‐year‐old standardbred colt with multicentric diffuse large B cell lymphoma

open access: yesEquine Veterinary Education, EarlyView.
Summary Lymphoma in horses is uncommon and rarely diagnosed as a cause of ataxia. This case report describes a 2‐year‐old Standardbred cryptorchid colt who presented with acute onset of grade 3–4/5 spinal ataxia in all four limbs, with the hindlimbs more severely affected than forelimbs and severe proprioceptive deficits.
K. MacMillan   +3 more
wiley   +1 more source

Use of a 3D‐printed custom‐designed tracheostomy tube to stabilise a permanent tracheostoma in a 25‐year‐old Icelandic mare

open access: yesEquine Veterinary Education, EarlyView.
Summary A 25‐year‐old Icelandic mare diagnosed with bilateral temporohyoid‐osteoarthropathy, moderate pharyngeal instability and bilateral laryngeal paralysis was presented because of intermittent stridor and dyspnoea worsening during exercise. As a previous ceratohyoidectomy had not improved these symptoms substantially, a permanent tracheostomy was ...
D. C. Debald   +3 more
wiley   +1 more source

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