Results 61 to 70 of about 70,402 (215)

Longitudinal trends in Gamma Knife radiosurgery utilization across multiple technological generations: A Single‐Institution Observational Study

Journal of Applied Clinical Medical Physics, Volume 27, Issue 10, October 2026.
Abstract Background Gamma Knife radiosurgery (GKRS) has been a foundational modality for the treatment of intracranial diseases for several decades, with successive platform generations introducing substantial technological advancements. Improvements in source configuration, patient positioning systems, imaging guidance, and immobilization techniques ...
Daniel El Basha, Eric Filiput, Austen Curcuru, Sven Ferguson, Sreekrishna Murty Goddu, Nels Knutson, Hugh Lee, Timothy Mitchell, Seungjong Oh, Joshua L. Dowling, Jiayi Huang, Taeho Kim   +11 more
wiley   +1 more source

Understanding the Symptom Burden of Complex Skull Base Tumors From the Patient's Perspective

Head &Neck, Volume 48, Issue 10, Page 2720-2732, October 2026.
ABSTRACT Background Symptom burden of skull base tumor (SBT) patients, especially those undergoing multimodality treatment, is poorly understood. We aim to understand symptom burden in this patient group using the core module the MD Anderson Symptom Inventory (MDASI).
Shirley Y. Su, Matheus Sewastjanow‐Silva, Jack Phan, Marc‐Elie Nader, Shaan M. Raza, Franco DeMonte, Paul W. Gidley, Ehab Y. Hanna, Loretta A. Williams   +8 more
wiley   +1 more source

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source

Prediction of blood supply in vestibular schwannomas using radiomics machine learning classifiers

Scientific Reports, 2021
This study attempts to explore the radiomics-based features of multi-parametric magnetic resonance imaging (MRI) and construct a machine-learning model to predict the blood supply in vestibular schwannoma preoperatively. By retrospectively collecting the
Dixiang Song, Yixuan Zhai, Xiaogang Tao, Chao Zhao, Minkai Wang, Xinting Wei   +5 more
doaj   +1 more source

The Case for Master Protocols for Rare Neurological Diseases

Annals of Neurology, Volume 100, Issue 3, Page 477-486, September 2026.
Master protocol trials allow for simultaneous multiple hypothesis testing within a common framework and might be applicable for rare diseases. In May 2025, the Network for Excellence in Neuroscience Clinical Trials convened a multistakeholder conference to discuss master protocol trials in rare neurological disorders.
Jennifer Vermilion, Sabrina Paganoni, Scott R. Plotkin, Melanie Quintana, Sara B. Calvert, Ineka T. Whiteman, Raymond Y. Wang, Nadia Moore, Erika F. Augustine   +8 more
wiley   +1 more source

Distinct spontaneous shrinkage of a sporadic vestibular schwannoma

, 2013
We present a case with outspoken spontaneous vestibular schwannoma shrinkage and review the related literature. The patient was initially diagnosed with a left-sided, intrameatal vestibular schwannoma, which subsequently grew into the cerebello-pontine ...
Huang, Xiaowen, Cayé-Thomasen, Per, Stangerup, Sven-Eric   +2 more
core   +1 more source

Vestibular function and quality of life in vestibular schwannoma: does size matter?

Frontiers in Neurology, 2011
Objectives. Patients with vestibular schwannoma (VS) frequently suffer from disabling vestibular symptoms. This prospective follow-up study evaluates vestibular and auditory function and impairment of quality of life due to vertigo, dizziness and ...
Judith eWagner, Miriam eGlaser, Berndt eWowra, Alexander eMuacevic, Roland eGoldbrunner, Christian eCnyrim, Jörg-Christian eTonn, Michael eStrupp   +7 more
doaj   +1 more source

Simultaneous Acquisition of Magnetic Resonance Elastography (MRE) and Diffusion Tensor Imaging (DTI) Optimized for Human Brain

Magnetic Resonance in Medicine, Volume 96, Issue 3, Page 1111-1120, September 2026.
ABSTRACT Purpose Increase clinical acceptance of MRE and DTI by shortening the scan time by half and providing diffusive and mechanical property maps that are inherently co‐registered. This proof‐of‐concept study evaluates the simultaneous DTI‐MRE acquisition in the human brain and compares its results to conventional DTI and MRE measurements.
Shujun Lin, Bradley P. Sutton, Richard L. Magin, Aaron T. Anderson, Dieter Klatt   +4 more
wiley   +1 more source

Effects of Asymmetric Auditory Deprivation in Sequential Cochlear Implant

Otolaryngology–Head and Neck Surgery, Volume 175, Issue 3, Page 672-681, September 2026.
Abstract Objective To evaluate the influence of auditory deprivation on sequential cochlear implants in postlingual patients, comparing the ear with shorter deprivation (ESAD), longer deprivation (ELAD), and the bilateral condition (BIL). Study design Retrospective study. Setting A tertiary referral center.
Eduardo S. Farinazzo, Rubens V. de Brito Neto, Elisabete H. Yamaguti, Marco A. Fornazieri, Luiz F. M. Lourençone   +4 more
wiley   +1 more source

A Protocol for Reconstructing Complex Lateral Skull Base Defects: Two Decades of Tertiary Care Experience

Otolaryngology–Head and Neck Surgery, Volume 175, Issue 3, Page 587-593, September 2026.
Abstract Objective To describe a multidisciplinary protocol for the resection and reconstruction of complex lateral skull base pathology, based on over two decades of experience in a high‐volume tertiary referral center in the United Kingdom. Study Design Retrospective descriptive analysis of institutional practice. Setting A high‐volume tertiary skull
Muhammad Umar Farooq, Yuri Hirayama, Jameel Muzaffar, Raghu Kumar, Charlie Huins, Peter Monksfield, James Baden, Demetrius Evriviades, Richard Irving   +8 more
wiley   +1 more source