Results 41 to 50 of about 112,219 (308)

Towards an Implantable Vestibular Prosthesis: The Surgical Challenges [PDF]

open access: yes, 2007
Published ...
Constandinou, T G   +3 more
core   +1 more source

Rational Design of Inner Ear Drug Delivery Systems

open access: yesAdvanced Science, EarlyView.
Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu   +5 more
wiley   +1 more source

Vestibular modulation of spatial perception [PDF]

open access: yes, 2013
Vestibular inputs make a key contribution to the own sense of spatial location. While the effects of vestibular stimulation on visuo-spatial processing in neurological patients have been extensively described, the normal contribution of vestibular ...
Elisa Raffaella Ferre   +4 more
core   +3 more sources

Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications

open access: yesAdvanced Science, EarlyView.
HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang   +5 more
wiley   +1 more source

Vestibular toxicity of cis-2-pentenenitrile in the rat [PDF]

open access: yes, 2013
cis-2-Pentenenitrile, an intermediate in the synthesis of nylon and other products, causes permanent behavioral deficits in rodents. Other low molecular weight nitriles cause degeneration either of the vestibular sensory hair cells or of selected ...
Balbuena   +39 more
core   +1 more source

Neuropharmacology of Vestibular System Disorders [PDF]

open access: yesCurrent Neuropharmacology, 2010
This work reviews the neuropharmacology of the vestibular system, with an emphasis on the mechanism of action of drugs used in the treatment of vestibular disorders. Otolaryngologists are confronted with a rapidly changing field in which advances in the knowledge of ionic channel function and synaptic transmission mechanisms have led to the development
Rosario Vega, Enrique Soto
openaire   +3 more sources

The State of High‐Resolution Imaging of the Human Inner Ear: A Look Into the Black Box

open access: yesAdvanced Science, EarlyView.
High‐resolution imaging of the cochlea is challenged by numerous unique aspects of this organ, where sensorineural cells, crucial for hearing, are too small for conventional modalities like magnetic resonance imaging and computed tomography. This article reviews current imaging techniques, emerging technologies, and innovations aimed at improving ...
Shelley Batts   +3 more
wiley   +1 more source

Small Extracellular Vesicles Orchestrate Cisplatin‐Induced Ototoxicity: Potential Biomarker and Targets Discovery

open access: yesAdvanced Science, EarlyView.
Cisplatin causes reactive oxygen species accumulation, leading to apoptosis and inflammation in cochlear hair cells. Small extracellular vesicles primarily derived from the damaged hair cells likely contribute to cisplatin‐induced ototoxicity, carrying a variety of microRNAs and proteins.
Jingru Ai   +14 more
wiley   +1 more source

Vestibular contribution to the planning of reach trajectories [PDF]

open access: yes, 2018
Reaching for an object while simultaneously rotating induces Coriolis and centrifugal inertial forces on the arm that require compensatory actions to maintain accuracy.
Bockisch, Christopher   +1 more
core  

Electrical vestibular stimuli evoke robust muscle activity in deep and superficial neck muscles in humans [PDF]

open access: yes, 2018
Neck muscle activity evoked by vestibular stimuli is a clinical measure for evaluating the function of the vestibular apparatus. Cervical vestibular-evoked myogenic potentials (cVEMP) are most commonly measured in the sternocleidomastoid muscle (and more
Blouin, J.-S. (Jean-Sébastien)   +3 more
core   +2 more sources

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