Results 61 to 70 of about 3,758 (187)

Greater Cochlear Damage in Otogenic Versus Meningogenic Meningitis: Hearing Rehabilitation Implications

open access: yesThe Laryngoscope, EarlyView.
Otogenic route of meningitis was associated with greater cochlear hair cell loss in comparison with the meningogenic one in this otopathology study. Neuronal depletion has been traditionally implicated in failed hearing rehabilitation of post‐meningitis deafness.
Matheus Pedrosa Tavares   +5 more
wiley   +1 more source

Rapid adaptation of multisensory integration in vestibular pathways

open access: yesFrontiers in Systems Neuroscience, 2015
Sensing gravity is vital for our perception of spatial orientation, the control of upright posture, and generation of our every day activities. When an astronaut transitions to microgravity or returns to earth, the vestibular input arising from self ...
Jerome eCarriot   +2 more
doaj   +1 more source

Synchrotron‐Based Deep Learning Network of the Inner Ear: Development and Expert Validation

open access: yesThe Laryngoscope, EarlyView.
A deep learning network to automatically segment the inner ear from preoperative clinical scans was developed using synchrotron‐radiation phase contrast imaging (SR‐PCI). On an unseen test set, the network significantly outperformed seven expert otologists/radiologists, the mean expert segmentation, and a simultaneous truth and performance level ...
Ashley Micuda   +11 more
wiley   +1 more source

Advances in GPCRs Associated With Wnt Signaling Within the Auditory System

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT G protein‐coupled receptors (GPCRs) that interact with the Wnt signaling pathway are pivotal for auditory system homeostasis, as they orchestrate inner ear development, hair cell (HC) regeneration, and hearing preservation. Frizzled (FZD) receptors, the core Wnt‐related GPCRs, bind Wnt ligands and co‐receptors (e.g., LRP5/6) to activate both ...
Liang Wang   +3 more
wiley   +1 more source

On the Representative CT Image of an Otic-Disrupting Fracture

open access: yesPhilippine Journal of Otolaryngology Head and Neck Surgery, 2020
Dear Editor: In the article entitled “Facial Paralysis in Longitudinal versus Oblique and Otic-Sparing versus Non Otic-Sparing Temporal Bone Fracture” published in the Vol 34 No 2 issue of the Philippine Journal of Otolaryngology Head and Neck Surgery,
Nathaniel Yang
doaj   +1 more source

Progress On Sensorineural Hearing Loss: Mechanisms and Therapies

open access: yesSensory Neuroscience, EarlyView.
ABSTRACT Hearing loss is the most common disabling disease among humans, which adversely affects human health. Sensorineural hearing loss (SNHL) accounting for approximately 63% of all hearing loss cases. SNHL may be classified into age‐related hearing loss (ARHL), drug‐induced hearing loss (DIHL), noise‐induced hearing loss (NIHL), and sudden ...
Yuan Zhang   +9 more
wiley   +1 more source

Developmental changes of ENaC expression and function in the inner ear of pendrin knock-out mice as a perspective on the development of endolymphatic hydrops. [PDF]

open access: yesPLoS ONE, 2014
Pendrin mutations cause enlarged vestibular aqueducts and various degrees of sensorineural hearing loss. The selective abolition of pendrin causes dilation of the membranous labyrinth known as endolymphatic hydrops, loss of the endocochlear potential ...
Bo Gyung Kim   +6 more
doaj   +1 more source

AMPKα Silencing Prevents Kanamycin‐Induced Ototoxicity in an Acute Mouse Model

open access: yesSensory Neuroscience, EarlyView.
Kanamycin plus furosemide (KM + FU) treatment (acute ototoxic model) causes AMPKα activation and rapidly induces cochlear outer hair cell (OHC) loss. Silencing AMPKα1 via posterior semicircular canal injection 48 h before KM + FU treatment reduces this damage, preserving OHCs and hearing.
Shengyu Zou   +6 more
wiley   +1 more source

Brain‐Inspired Neuromorphic Device for Artificial Intelligent Robots Applications

open access: yesSmartBot, EarlyView.
Brain‐inspired neuromorphic devices mimic biological systems to provide an efficient hardware foundation for embodied intelligent robotics. This review explores the material systems and corresponding computing architectures of neuromorphic devices that support low‐power perception, adaptive learning, and real‐time decision‐making.
Jiachen Han   +3 more
wiley   +1 more source

Subjective Visual Vertical Can be an Effective Tool to Evaluate Vestibular Function of Stapedotomy

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective To investigate if the subjective visual vertical/horizontal (SVV/SVH) can be used to evaluate the otolith organ of otosclerosis and stapedotomy. Design A total of 19 patients who were diagnosed with otosclerosis and underwent surgical treatment in our hospital were collected.
Tao Jiang, Juan Zheng, Wen‐Yan Li
wiley   +1 more source

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