Results 11 to 20 of about 70,503 (403)
Block of NMDA receptor channels by endogenous neurosteroids: implications for the agonist induced conformational states of the channel vestibule [PDF]
Scientific Reports, 2015 N-methyl-D-aspartate receptors (NMDARs) mediate synaptic plasticity, and their dysfunction is implicated in multiple brain disorders. NMDARs can be allosterically modulated by numerous compounds, including endogenous neurosteroid pregnanolone sulfate ...
A Malayev +61 more
core +2 more sources
eLife, 2020 Pentameric ligand-gated ion channels (pLGICs) or Cys-loop receptors are involved in fast synaptic signaling in the nervous system. Allosteric modulators bind to sites that are remote from the neurotransmitter binding site, but modify coupling of ligand ...
Marijke Brams +12 more
doaj +2 more sources
Evaluation of Staging Systems for Cancer of the Nasal Vestibule
Cancers, 2023 Simple Summary Cancer of the nasal vestibule is thought to be rare. Multiple staging systems exist for the staging of these tumors, which can lead to variability and, therefore, the poor reliability of data.
W. F. J. Scheurleer +10 more
semanticscholar +1 more source
Hybrid Deep Feature Fusion of 2D CNN and 3D CNN for Vestibule Segmentation from CT Images
Computational and Mathematical Methods in Medicine, 2022 The accurate vestibule segmentation from CT images is essential to the quantitative analysis of the anatomical structure of the ear. However, it is a challenging task due to the tiny size, blur boundary, and drastic variations in shape and size.
Ruicong Zhang +5 more
semanticscholar +1 more source
Ophiorrhiza shiqianensis (Rubiaceae), a new species from Guizhou, China [PDF]
PhytoKeys, 2019 A new species of the genus Ophiorrhiza L. (Rubiaceae), Ophiorrhiza shiqianensis L.D.Duan & Yun Lin, is described, illustrated and photographed from Shiqian County, Guizhou Province, South-western China.
Lin-Dong Duan, Yun Lin, Zhen Lu
doaj +3 more sources
A Comprehensive Literature Review on the Architecture of the Upper Labial Frena [PDF]
International Journal of Anatomy Radiology and Surgery, 2021 Over the past few years, various surgical procedures have evolved that focus on releasing the taut superior labial frena in infants, yet little is known about their normal or variant morphology despite the growing incidence of severe upper labial frenar
S Surraj +4 more
doaj +1 more source
Age-Related Changes in the Cochlea and Vestibule: Shared Patterns and Processes
Frontiers in Neuroscience, 2021 Both age-related hearing loss (ARHL) and age-related loss in vestibular function (ARVL) are prevalent conditions with deleterious consequences on the health and quality of life. Age-related changes in the inner ear are key contributors to both conditions.
V. Paplou, Nick M A Schubert, S. Pyott
semanticscholar +1 more source
Pharmaceutics, 2023 The causes of vestibular dysfunction include the loss of hair cells (HCs), synapses beneath the HCs, and nerve fibers. 7, 8–dihydroxyflavone (DHF) mimics the physiological functions of brain-derived neurotrophic factor. We investigated the effects of the
Makoto Kinoshita +4 more
doaj +1 more source
Multidisciplinary approach to nose vestibule malignancies: setting new standards
Acta otorhinolaryngologica italica, 2021 SUMMARY Nose vestibule malignancies, mainly SCCs, are considered rare neoplasms. In the present paper, we review the current state of the art concerning classification and treatment, and describe current evidence supporting a paradigm shift.
F. Bussu +7 more
semanticscholar +1 more source
E-Spania, 2021 Ce travail propose une réflexion sur les seuils métaphoriques du livre (son vestibule, ses portes de passage ou de clôture), en vue d’approfondir sur la conception du livre lui- même, ses fonctions et les problèmes de commercialisation, de création et de
Soledad Arredondo
doaj +1 more source