Results 51 to 60 of about 2,474,802 (240)

A narrative review of veterinary pharmacovigilance situations and prospects in East African countries

Frontiers in Veterinary Science
BackgroundVeterinary pharmaceuticals must be safe and effective for treating and preventing diseases in animal sectors. Strict adherence to regulations at every stage of production, storage, and administration is necessary as the global sector grows in ...
Yesuneh Tefera Mekasha, Sete Nigussie, Abibo Wondie Mekonen, Kassahun Berrie, Asnakew Mulaw, Melaku Getahun Feleke   +5 more
doaj   +1 more source

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

Veterinary Genetics Laboratory, Onderstepoort, Faculty of Veterinary Science, Issue 1 [PDF]

, 2014
Originally published as HTML file, converted to PDF with Adobe Acrobat 9 Pro Version 9.0.0.News articles with colour photos from the Veterinary Genetics Laboratory (VGL) to highlight the contribution that the University of Pretoria is making in terms of ...
University of Pretoria. Faculty of Veterinary Science. Veterinary Genetics Laboratory
core   +1 more source

Corridor of the Veterinary Large Animal Medicine Building

, 1993
Elias E. Perris, who was a veterinary clinical associate with Large Animal Medicine, examines horse and instructs students in the corridor. Physical description: color prints (photographs), 22.5X15mmAs of 2017 Dr. Elias E.
Morgan , Beth Media Resources, College of Veterinary Medicine
core   +1 more source

Nanoparticles for antiparasitic drug delivery

Drug Delivery, 2019
As an emerging novel drug carrier, nanoparticles provide a promising way for effective treatment of parasitic diseases by overcoming the shortcomings of low bioavailability, poor cellular permeability, nonspecific distribution and rapid elimination of ...
Yuzhu Sun, Dongmei Chen, Yuanhu Pan, Wei Qu, Haihong Hao, Xu Wang, Zhenli Liu, Shuyu Xie   +7 more
doaj   +1 more source

Gene Correction Enhances Dopaminergic Cell Therapy in a Nonhuman Primate Model of Parkinson's Disease

Advanced Science, EarlyView.
LRRK2‐mutant induced pluripotent stem cells (iPSCs) were derived from a patient with Parkinson's disease (PD). Using CRISPR/Cas9–mediated gene editing, the pathogenic LRRK2 mutations were precisely corrected, and isogenic dopaminergic neural progenitor cells (DA‐NPCs) were subsequently generated.
Qing Yan, Chongchong Xu, Jiangmei Gao, Pu Wang, Qingling Wu, Ying Jin, Binyan Lu, Mu Li, Mingting Shao, Bihai Li, Zhenghui Su, Yijng Zhang, Jianhuan Chen, Haojie An, Mengyao Huang, Xiaoji Zhuang, Yuhui Shen, Fenglin Wang, Nana Xu, Yiyan Liu, Lei Tang, Xiuling Zhong, Minyan Zhong, Jiecong Chen, Zhenhuang Wang, Xingrong Luo, Sheng Liu, RuiFeng Liu, Ling Zhang, Junhua Rao   +29 more
wiley   +1 more source

Establishment of an indirect ELISA antibody detection method based on the stable expression of LSDV P32 protein in CHO-K1 cells

BMC Biotechnology
Background Lumpy skin disease (LSD), caused by infection with the lumpy skin disease virus (LSDV), is a highly infectious disease that poses a notable challenge to the cattle industry worldwide.
Ruolan Xin, Jiawen Zhang, Yinghui Zhang, Daoming Su, Menglin Li, Dan Liu, Ruizhi Wu, Junjie Zhao, Yuanyuan Zhu, Yebing Liu, Xiaoyun Chen, Yongjun Wen, Zhen Zhu   +12 more
doaj   +1 more source

Introducing Borsantrazole: A Trifunctional Boron‐Based Pyrazole That Extends the Lifespan of Amyotrophic Lateral Sclerosis Mice

Advanced Science, EarlyView.
Herein we report a boron‐based pyrazole, (Borsantrazole ‐ a small molecule that selectively targets oxidative stress) that significantly increases survival, reduces weight loss, delays disease onset, and affects global protein changes in the SOD1‐G37R mouse model of ALS.
Nitesh Sanghai, Rhonda Kelley, Ying Lao, M. Immanuel Reyes Madlangsakay, Prasanta Paul, M. Alejandra Llanes‐Cuesta, Jun‐Feng Wang, René P. Zahedi, Jiming Kong, Geoffrey K. Tranmer   +9 more
wiley   +1 more source

Transdermal Drug Delivery System in Veterinary Practice: An Overview [PDF]

, 2011
In veterinary practice drug delivery strategies are complicated by species diversity, body size variations, cost constraints and level of convenience.
Dimri, U., Kumar, P., Dar, A. A., Sharma, M. C., Ansari, A. A.   +4 more
core   +1 more source

Cornell Veterinary Medicine, Winter 1999-2000 [PDF]

, 2000
Cornell Veterinary Medicine, Winter 1999-2000Topics of articles in this issue of Cornell Veterinary Medicine include: Scientists Uncover Structure of Essential Protein Complex: A Key Step Toward Cancer-Fighting Drugs; Cornell's Veterinary Legacy (Donald ...
Cornell University. College of Veterinary Medicine, Wall, Jeri   +1 more
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