Results 71 to 80 of about 1,695,240 (291)

A Practical Framework for ASFV Disinfectant Evaluation: Differentiating Cytopathic Effects from Cytotoxicity via Integrated Analytical Methods

Pathogens
African swine fever virus (ASFV) is a highly virulent DNA virus that has spread globally since its introduction into Georgia in 2007, causing substantial economic losses in the swine industry. In the absence of an effective vaccine, chemical disinfection
Sok Song, Kyu-Sik Shin, Su-Jeong Kim, Yong Yi Joo, Bokhee Han, So-Hee Park, Hyun-Ok Ku, Wooseog Jeong, Choi-Kyu Park   +8 more
doaj   +1 more source

Authorisation procedures for veterinary medicinal produscts and application types [PDF]

Medicamentul Veterinar, 2009
The authorization process of veterinary medicinal products is an complex and laborious process, which is accomplished through multiple stages and by centralized procedures, communitary or nationals in the respect of 2001/82/EC Directive amended by the ...
Alina Karina Draghici,, Lollita Taban
doaj  

Cytokine response to the RSV antigen delivered by dendritic cell-directed vaccination in congenic chicken lines

Veterinary Research, 2017
Systems of antigen delivery into antigen-presenting cells represent an important novel strategy in chicken vaccine development. In this study, we verified the ability of Rous sarcoma virus (RSV) antigens fused with streptavidin to be targeted by specific
Jitka Mucksová, Jiří Plachý, Ondřej Staněk, Jiří Hejnar, Jiří Kalina, Barbora Benešová, Pavel Trefil   +6 more
doaj   +1 more source

Bioinspired Passive Flow Routing to Mitigate Thrombosis in Prosthetic Heart Valves and Cardiovascular Devices

Advanced Science, EarlyView.
Bioinspired passive flow routing mitigates thrombosis in cardiovascular devices by redirecting a small fraction of forward flow into stagnation‐prone regions. Inspired by avian alula and aircraft slat mechanisms, strategically placed routing channels restore washout around mechanical heart valves, reducing low‐shear exposure by four orders of magnitude
Yevgeniy Kreinin, Mark Epshtein, Yahel Talmon, Tirosh Mekler, Itay Or, Mahli Raad, Gil Bolotin, Josué Sznitman, Netanel Korin   +8 more
wiley   +1 more source

Antiviral effects of Codonopsis pilosula extract and its bioactive components against porcine epidemic diarrhea virus in vitro via the AMPK/mTOR pathway

BMC Veterinary Research
Background Porcine Epidemic Diarrhea Virus (PEDV) frequently outbreaks across China, posing a significant economic threat to the swine industry. PEDV exhibits a high degree of variability and is associated with a high mortality rate in piglets. Currently,
Tao Ren, Shiqin Pan, Xuqin Song, Liting Cao, Anchun Cheng, Yujie Zhan, Jian Yang, Deyuan Ou   +7 more
doaj   +1 more source

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

Concentration- and Time-Dependent Virucidal Responses of Major Transboundary Animal Disease Viruses to Disinfectants

Viruses
Transboundary animal diseases (TADs) pose persistent threats to global livestock production, and chemical disinfection remains a critical component of biosecurity.
Sok Song, So-Hee Park, Kyu-Sik Shin, Hyun-Ok Ku, Wooseog Jeong   +4 more
doaj   +1 more source

Rapid sexing of selected Galliformes by polymerase chain reaction

Czech Journal of Animal Science, 2012
Vent sexing of one-day-old chicks in commercial hatcheries has long been common practice and can be highly accurate. However, there are circumstances when this technique is not applicable such as smaller breeds, non-domestic birds, or where is the ...
J. Kalina, J. Mucksová, H. Yan, P. Trefil   +3 more
doaj   +1 more source

Lab reports and cat scans: can veterinary oncology guide our way to new treatments for human cancers? [PDF]

, 2012
The development of veterinary oncology as a speciality has benefited from the changing role of companion animals in society, and the accessibility to treatment afforded by pet insurance schemes now means that, at least in financial terms, a ...
Airley, Rachel
core   +1 more source

Gene Correction Enhances Dopaminergic Cell Therapy in a Nonhuman Primate Model of Parkinson's Disease

Advanced Science, EarlyView.
LRRK2‐mutant induced pluripotent stem cells (iPSCs) were derived from a patient with Parkinson's disease (PD). Using CRISPR/Cas9–mediated gene editing, the pathogenic LRRK2 mutations were precisely corrected, and isogenic dopaminergic neural progenitor cells (DA‐NPCs) were subsequently generated.
Qing Yan, Chongchong Xu, Jiangmei Gao, Pu Wang, Qingling Wu, Ying Jin, Binyan Lu, Mu Li, Mingting Shao, Bihai Li, Zhenghui Su, Yijng Zhang, Jianhuan Chen, Haojie An, Mengyao Huang, Xiaoji Zhuang, Yuhui Shen, Fenglin Wang, Nana Xu, Yiyan Liu, Lei Tang, Xiuling Zhong, Minyan Zhong, Jiecong Chen, Zhenhuang Wang, Xingrong Luo, Sheng Liu, RuiFeng Liu, Ling Zhang, Junhua Rao   +29 more
wiley   +1 more source