Results 51 to 60 of about 103,029 (263)

O estado da arte na determinação de resíduos de medicamentos veterinários em alimentos de origem animal empregando técnicas cromatográficas acopladas à espectrometria de massas

Química Nova, 2013
The determination of veterinary drug residues in foods of animal origin is an important issue because of the risk these compounds pose to human health in addition to their persistence and tendency to bioaccumulate.
Osmar D. Prestes, Manoel L. Martins, Caroline do A. Friggi, Juliana S. Munaretto, Martha B. Adaime, Renato Zanella   +5 more
doaj   +1 more source

Stretchable Microelectrode Arrays with Microneedles for Reliable Electrophysiological Recording of Human Heart and Brain Organoids

Advanced Science, EarlyView.
A stretchable 3D microelectrode array with microneedles (3D MN‐sMEA) enables stable, minimally destructive electrophysiological monitoring of 3D organoids. The wafer‐level stud‐bump bonding process facilitates high‐fidelity recordings of heart and cerebral organoids.
Eunyoung Jang, Saewoon Shin, Seul‐Gi Lee, Kiup Kim, Yoojeong Kim, Jun Sun, Il‐Joo Cho, Joseph A. Gogos, Jong‐Chan Park, C‐Yoon Kim, Hyunjoo J. Lee   +10 more
wiley   +1 more source

Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes

Advanced Science, EarlyView.
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami, Masanori Ono, Yasunari Mizumoto, Tatsuhito Kanda, Takashi Iizuka, Takiko Daikoku, Shin‐ichi Horike, Akira Hattori, Akihito Horie, Sachiko Minamiguchi, Tomoko Fujiwara, Kazuyoshi Hosomichi, Atsushi Tajima, Hirokazu Usui, Kaoru Abiko, Hiroshi Fujiwara   +15 more
wiley   +1 more source

Immune-Enhancing Effect of Acanthopanax gracilistylus W. W. Smith Polysaccharides and Liposomes as Dilutions of Chicken Newcastle Disease Vaccine

Animals
Acanthopanax gracilistylus W. W. Smith is a traditional Chinese herbal medicine that contains a variety of bioactive components, including polysaccharides. In this study, a polysaccharide was extracted from A.
Linjie Huang, Qi Tang, Jiayi Li, Zhaolong Li, Kai Chen, Yijiong Tao, Lifang Zhang, Chenzhong Fei, Yinchun Liu, Keyu Zhang, Mi Wang   +10 more
doaj   +1 more source

Toxicity testing of the veterinary use drugs [PDF]

Medicamentul Veterinar, 2007
Before the authorization for comercialization both medical and phyto-sanitary products must be tested for inocuity and toxicity, the risk assesment for persons working in drug industry, pharmacy, human beings and animals treated with the product and for ...
Solcan Gh.,, Beschea Chiriac I. S.,
doaj  

p300 Degradation by the p53‐SIAH1 Axis Relieves TBK1 Acetylation to Enhance Innate Antiviral Immunity

Advanced Science, EarlyView.
This study identifies p300 as the acetyltransferase that acetylates TBK1 and inhibits its phosphorylation. Activation of the p53‐SIAH1 axis by immune response downregulates p300 expression to sustain innate antiviral immunity. Conditional p300 knockout in alveolar epithelial cells in vivo promotes antiviral responses and suppresses virus replication ...
Huidi Yu, Zhihao Zhan, Xiaoxiang Pan, Xinyue Zhang, Penggang Liu, Jing Sun, Xiulong Xu   +6 more
wiley   +1 more source

Authorisation procedures for veterinary medicinal produscts and application types [PDF]

Medicamentul Veterinar, 2009
The authorization process of veterinary medicinal products is an complex and laborious process, which is accomplished through multiple stages and by centralized procedures, communitary or nationals in the respect of 2001/82/EC Directive amended by the ...
Alina Karina Draghici,, Lollita Taban
doaj  

ZNF33B Promotes Japanese Encephalitis Virus Infection by Regulating the Stability of M6A‐Modified Trim25 to Control the Autophagy Process

Advanced Science, EarlyView.
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du, Chunwei Li, Jiyuan Luo, Huizhi Zhang, Jinyan Zhang, Suya Wang, Huanchun Chen, Hongli Xu, Xiangmin Li, Ping Qian   +9 more
wiley   +1 more source

A Practical Framework for ASFV Disinfectant Evaluation: Differentiating Cytopathic Effects from Cytotoxicity via Integrated Analytical Methods

Pathogens
African swine fever virus (ASFV) is a highly virulent DNA virus that has spread globally since its introduction into Georgia in 2007, causing substantial economic losses in the swine industry. In the absence of an effective vaccine, chemical disinfection
Sok Song, Kyu-Sik Shin, Su-Jeong Kim, Yong Yi Joo, Bokhee Han, So-Hee Park, Hyun-Ok Ku, Wooseog Jeong, Choi-Kyu Park   +8 more
doaj   +1 more source

CauFinder: Steering Cell‐State and Phenotype Transitions by Causal Disentanglement Learning

Advanced Science, EarlyView.
CauFinder combines causal disentanglement modeling and network control to prioritize causal drivers of cell‐state transitions from observational transcriptomic data. The framework separates transition‐relevant signals from spurious associations, nominates intervention targets across biological and disease contexts, and identifies DAAM1 as an actionable
Chengming Zhang, Zexi Chen, Yuanxiang Miao, Zuolin Shen, Deyu Cai, Shijie Tang, Yun Xue, Weifeng Guo, Hongbin Ji, Jian Liu, Kazuyuki Aihara, Luonan Chen   +11 more
wiley   +1 more source