Results 121 to 130 of about 27,865,843 (231)

Long Noncoding RNA PCALRx Interacts with Pyruvate Carboxylase to Drive Multi‐Organ Developmental Toxicity in Zebrafish Embryos Exposed to Amoxicillin

Advanced Science, EarlyView.
Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao, Ping Jiang, Xinli Zhou, Mengying Yin, Qiong Luo, Hui Wang   +5 more
wiley   +1 more source

Community Engagement newsletter, Faculty of Veterinary Science, Summer, February 2018 [PDF]

, 2018
News articles with colour photos about the various community engagement projects of the Faculty of Veterinary Science, University of Pretoria.Community education on small scale chicken farming / Mareli Smalberger -- Hluvukani experience / Elza Hollenbach,
Venter, Anke, Millar, Kenja-Lee, Van Wyk, Ivan, Teffu, Lesego, Greeff, Carrea, Machimana, Eugene Gabriel, Hollenbach, Elza, Buongiorno, Fladia, Van heerden, Melyssa, Smalberger, Mareli, Smit, Lindi, Domenico, Samantha   +11 more
core  

Cytotoxicity and physicochemical characterization of iron–manganese-doped sulfated zirconia nanoparticles [Corrigendum]

International Journal of Nanomedicine, 2015
Al-Fahdawi MQ, Rasedee A, Al-Qubaisi MS, et al. Int J Nanomedicine. 2015;10:5739–5750.On page 5739, Affiliation section, the affiliations "1Institute of Bioscience, 2Department of Veterinary Pathology and Microbiology, Faculty of Veterinary ...
Al-Fahdawi MQ, Rasedee A, Al-Qubaisi MS, Alhassan FH, Rosli R, El Zowalaty ME, Naadja SE, Webster TJ, Taufiq-Yap YH   +8 more
doaj  

AARS1‐Mediated RUNX3 K193 Lactylation Enhances the Activation and Cytotoxicity of CD8+T Cells in Smoking‐Related Emphysema

Advanced Science, EarlyView.
Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu, Jiaheng Lin, Yifan Li, Qiaoqiao Zhou, Min Yu, Cheng Cheng, Kang Chang, Dang Lin, Tao Bian, Yan Wu, Lu Lu, Haibo Xia, Qizhan Liu   +12 more
wiley   +1 more source

Community Engagement newsletter, Faculty of Veterinary Science, Spring, 2011 [PDF]

, 2011
News articles with colour photos about the various community engagement projects of the Faculty of Veterinary Science, University of Pretoria.Community engagement project at VulPro / Cassie van der Walt, Jeanine Gautschi, Werner Wentzel, Luzanne Lourens,
Wentzel, Werner, Erasmus, Reinach, Liebenberg, C., Gautschi, Jeanine, Dommett, Lauren, Friedman, Stephanie, Braysher, Natalie, Lourens, Luzanne, Grundlingh, Daleen   +8 more
core  

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

Advanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch, Muhammad D. Ariadi, Min Jung Kwun, Leonie Howells, Saiveth Hernandez‐Hernandez, Nicholas J. Croucher, Pedro J. Ballester   +6 more
wiley   +1 more source

Immunohistochemical and molecular profiling of CD 117, Oct-4, and Sox-2 in canine cutaneous mast cell tumor of the crossbred dogs in Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand. [PDF]

Vet World, 2021
Meesuwan S, Ketpun D, Piyaviriyakul P, Rattanapinyopituk K, Theewasutrakul P, Sailasuta A.   +5 more
europepmc   +1 more source

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery

Advanced Science, EarlyView.
A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li, Jiao Qiao, Qiuyuan Zhang, Peipei Liu, Chenjun Zheng, Qi Zhou, Mengqi Ji, Zhihui Zhu, Xiaoxue Li, Hongyu Zhang   +9 more
wiley   +1 more source

Crossing the line? Reflecting on interdisciplinary boundaries in veterinary science. [PDF]

Vet Rec Open
Durán SM, Lamont K, Peshin S, Briceño C.   +3 more
europepmc   +2 more sources