Results 101 to 110 of about 5,997,135 (271)

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

Predictors of knowledge, attitude, and practices of anthrax prevention among selected veterinary students in Nigeria and Ghana

Discover Public Health
Background Anthrax is a zoonotic disease caused by a spore-forming bacterium called Bacillus anthracis. Globally, between 2000 and 20,000 human cases of anthrax are reported annually; however, measures such as vaccination have been put in place in some ...
Adelekan Oluseyi Okunlade, Hezekiah Kehinde Adesokan, Foluke Olajumoke Jemilehin, Aishat Motunrayo Oyatoye, Blessing Oluwakemi Ige, Adebola Olawumi Okunlade, Oladapo Oyedeji Oludairo, Oluwawemimo Oluseun Adebowale, Peter Ibukunoluwa Alabi, Derrick Adu Asare, Akinlabi Oladele Ogunleye, Benjamin Obukowho Emikpe   +11 more
doaj   +1 more source

Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery

Advanced Science, EarlyView.
A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li, Jiao Qiao, Qiuyuan Zhang, Peipei Liu, Chenjun Zheng, Qi Zhou, Mengqi Ji, Zhihui Zhu, Xiaoxue Li, Hongyu Zhang   +9 more
wiley   +1 more source

Assessment of the knowledge, attitudes and practices level on toxoplasmosis and its seroprevalence in selected high-risk groups in Cebu, Philippines

Frontiers in Veterinary Science
Toxoplasmosis, a zoonotic disease caused by Toxoplasma gondii, poses significant health risks, especially to high-risk individuals who are exposed to cats.
Adrian P. Ybañez, Adrian P. Ybañez, Grahambell B. Sabanate, Serafin L. Garciano, Ruby H. Destajo, Rochelle Haidee D. Ybañez, Rochelle Haidee D. Ybañez, Yoshifumi Nishikawa, Harvie P. Portugaliza   +8 more
doaj   +1 more source

Convergence of Plasmid‐Mediated tmexCD‐toprJ With Critical Resistance Genes Fuels Spread of Multidrug Resistant Bacteria

Advanced Science, EarlyView.
Global dissemination of tmexCD‐toprJ across bacterial hosts and ecological niches is accompanied by its convergence with blaKPC, blaNDM, and mcr on mobile plasmids. Recombination and acquisition of resistance modules generate distinct multidrug resistant plasmid architectures, facilitating the emergence and spread of high‐risk bacterial populations ...
Kaiwen Song, Meng Wang, Xingyu Wu, Meng Cai, Bowen Li, Qi Wang, Xiaodong Guan, Qi Ding, Ruobing Wang, Hui Wang   +9 more
wiley   +1 more source

Corridor of the Veterinary Large Animal Medicine Building

, 1993
Elias E. Perris, who was a veterinary clinical associate with Large Animal Medicine, examines horse and instructs students in the corridor. Physical description: color prints (photographs), 22.5X15mmAs of 2017 Dr. Elias E.
Morgan , Beth Media Resources, College of Veterinary Medicine
core   +1 more source

Loss of LCN2 Function Ameliorates Glucocorticoid‐Induced Muscle Atrophy via Remodeling the Extracellular Matrix

Advanced Science, EarlyView.
Glucocorticoids transcriptionally activate LCN2 expression via GR nuclear translocation. Secreted LCN2 binds MMP9 to degrade skeletal muscle ECM collagen, blocks integrin‐mediated mechanotransduction, bidirectionally disrupts muscle protein homeostasis, and reveals a novel target for steroid‐induced muscle atrophy.
Hongwei Shi, Xiaojing Hao, Yi Yan, Fengyang Li, Yaru Zhang, Zixin Li, Wenjuan Xie, Jiayin Lu, Xiaomao Luo, Yanjun Dong, Haidong Wang, Juan Wang   +11 more
wiley   +1 more source

Root‐Inspired Microneedle Patch With Interlocked Rigid‐Soft Architecture for High Tissue‐Adaptiveness

Advanced Science, EarlyView.
A root‐inspired microneedle array patch uses lattice‐based mechanical interlocking to unite rigid microneedles with a flexible substrate. The interlocked rigid–soft architecture improves interfacial bonding, supports stable adhesion on curved and wet tissues under dynamic motion, and provides a versatile platform for robust biointerfacing and future ...
Jongchan Lee, Yeongjun Song, Yonghyun Cho, Hyo In Kim, Dong‐Hyun Youn, Jinbong Park, Seungbeom Choi, Dohyun Kwon, Brian Jun Lee, Sangyul Baik   +9 more
wiley   +1 more source

CDK4/MERCs/PINK1 Axis Drives PFOA/HFPO‐TA‐Induced Cardiac Senescence via Mitophagy Defect and cGAS‐STING Activation: In Vitro Amelioration by Cycloastragenol

Advanced Science, EarlyView.
The present study demonstrated that PFOA and HFPO‐TA exposure suppressed CDK4, disrupted MERCs and impaired PINK1/Parkin‐mediated mitophagy, thereby accelerating cardiac senescence, whereas CAG effectively reversed these pathological changes in vitro. Our findings identify CDK4 as a critical regulator bridging mitophagy defects and cardiac senescence ...
Nuo‐Wa Li, Jun‐Ze Jiang, Ying‐Ying Liu, Tian‐Tian Zhang, Kanwar Kumar Malhi, Xin Yao, Jin‐Long Li   +6 more
wiley   +1 more source

Risk of zoonotic diseases among veterinary students in Nigeria: a multi-institutional national cross-sectional survey

Discover Public Health
Veterinary students are frontline professionals undergoing professional training and are at a high risk of contracting zoonotic diseases. However, little is known about their preparedness to address zoonotic risks in their future careers.
Ibraheem Ghali-Mohammed, Ayomide Samuel Afolayan, Akeem Adebola Bakare, Ridwan Olamilekan Adesola, Tajudeen Opeyemi Isola, Uduak Akpabio, Selim Adewale Alarape, Shuaibu Gidado Adamu, Nma Bida Alhaji, Ismail Ayoade Odetokun   +9 more
doaj   +1 more source