Results 121 to 130 of about 162,411 (307)

Bioorthogonal Fluorogenic Reporters for Noninvasive Imaging and Urinalysis of Immunotherapeutic Response in Renal Cell Carcinoma

Advanced Science, EarlyView.
This study reported renal‐clearable bio‐orthogonal near‐infrared fluorogenic probes (BGRs) that specifically imaging and urinalysis of granzyme B for dynamic evaluation of RCC immunotherapy. BGRs not only differentiate immunotherapeutic responses in orthotopic RCC mice, but also enable sensitive optical urinalysis of granzyme B in clinical specimens ...
Xingyue Yang, Baoshuai Liang, Liangmin Fu, Weiliang Deng, Yuyan Jiang, Weiping Xu, Jinwei Chen, Ya Zhou, Ke Wu, Jiaguo Huang   +9 more
wiley   +1 more source

EQUINE CLIENT SATISFACTION AT THE VETERINARY TEACHING HOSPITAL, MICHIGAN STATE UNIVERSITY--JULY 1, 1999 THROUGH JUNE 30, 2000 [PDF]

Understanding clients' wants and needs is vital to the sustained success of any service business, and veterinary medicine offers no exception. The Veterinary Teaching Hospital (VTH) at the Michigan State University College of Veterinary Medicine (MSU-CVM)
Camara, Youssouf, Donovan, Debra, Gross, Renee, Leeper, Delta, Lloyd, James W.   +4 more
core   +1 more source

Mechanistic Design of Graphdiyne‐Based Multimodal Sensing Integrating Machine Learning and Photothermal Dynamics for Precision Recognition and On‐Demand Inactivation

Advanced Science, EarlyView.
A triple‐mode theranostic platform enables integrated electrochemical, colorimetric, and photothermal detection of bacterial infection. Glucose oxidation triggers H2O2 generation and TMB oxidation to oxTMB, producing color and thermal signals under 808 nm NIR irradiation.
Jing Xu, Hanxiao Chen, Liucun Yin, Yifang Tao, Qichen Yuan, Hong Wang, Huan Pang, Junyan Teng, Li Xue   +8 more
wiley   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

Advanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao, Zian Wu, Xiaodong Wang, Yongheng Zhao, Wenkai Ke, Bowen Tan, Yun Liu, Youqiang Su, Wei Ren, Xiang Li, Changjiu He   +13 more
wiley   +1 more source

Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus

Advanced Science, EarlyView.
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan, Dong Zhou, Ran Shao, Xing Liu, Jin Peng, Yingran Huang, Shuhui Qi, Cankun Xi, Menghang Wang, Bin Sun, Yinglin Qi, Xin Yin   +11 more
wiley   +1 more source

Predictors of knowledge, attitude, and practices of anthrax prevention among selected veterinary students in Nigeria and Ghana

Discover Public Health
Background Anthrax is a zoonotic disease caused by a spore-forming bacterium called Bacillus anthracis. Globally, between 2000 and 20,000 human cases of anthrax are reported annually; however, measures such as vaccination have been put in place in some ...
Adelekan Oluseyi Okunlade, Hezekiah Kehinde Adesokan, Foluke Olajumoke Jemilehin, Aishat Motunrayo Oyatoye, Blessing Oluwakemi Ige, Adebola Olawumi Okunlade, Oladapo Oyedeji Oludairo, Oluwawemimo Oluseun Adebowale, Peter Ibukunoluwa Alabi, Derrick Adu Asare, Akinlabi Oladele Ogunleye, Benjamin Obukowho Emikpe   +11 more
doaj   +1 more source

A Dual‐Functional Biohybrid Nanorobot to Synergistically Eradicate Biofilm and Degrade Antibiotic Resistance Genes

Advanced Science, EarlyView.
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang, Tong Dou, Luokai Wang, Jingxian Yang, Wenrui Wang, Shuaitian Guo, Xiangyu Li, Xuefang Huang, Yunlei Xianyu, Dongsheng Wang   +9 more
wiley   +1 more source

The Berkshire College of Agriculture: report from the Inspectorate (FEFC inspection report; 108/97 and 01/00) [PDF]

, 2000
The Further Education Funding Council has a legal duty to make sure further education in England is properly assessed. The FEFC’s inspectorate inspects and reports on each college of further education according to a four-year cycle. This record comprises

core  

Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation

Advanced Science, EarlyView.
This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar, Yannaël Bossard, Rachel Sava, Tobias Gänswein, Lorenca Sadiraj, Jean‐Samuel Dupré, Manuel Schröter, J. Gray Camp, Fernando Cardes, Julian Bartram, Andreas Hierlemann   +10 more
wiley   +1 more source

Herbal folk remedies for animal health in the Netherlands [PDF]

, 2006
As a part of their training in herbalism 85 students of the two private schools for natural animal care that exist in the Netherlands were given the assignment to ask farmers, pet owners and animal pension keepers about their traditional remedies.
Beijer, Helen, Van Asseldonk, Drs. Tedje
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