Results 51 to 60 of about 929 (159)

A rare case of VEXAS syndrome. [PDF]

Rheumatol Adv Pract
Gupta K, El-Ghazali S, Kubba F.
europepmc   +3 more sources

Serum Cytokine Profiling Differentiates Underlying Diseases in Cytokine Storm Syndrome

Arthritis &Rheumatology, Volume 78, Issue 2, Page 463-474, February 2026.
Serum cytokine profiling was performed using Luminex (48 cytokines) and ELISA (5 cytokines). Assessment of key cytokines (IFN‐α, IL‐18, IL‐6, CXCL9) delineated five dominant inflammatory patterns: I, IFN‐α–dominant CSS; II, IL‐18–dominant CSS; III, IL‐6–dominant CSS; IV, IFN‐γ–dominant CSS; and V, IL‐6 & IFN‐γ intermediate CSS.
Shuya Kaneko, Maho Hatano, Asami Shimbo, Futaba Miyaoka, Hitoshi Irabu, Yuko Akutsu, Yuko Hayashi, Mao Mizuta, Yasuo Nakagishi, Keiji Akamine, Naomi Iwata, Kenji Furuno, Takayuki Tanaka, Kazuyuki Ueno, Shuhei Fujita, Koji Yokoyama, Toshinori Minato, Kazushi Izawa, Takahiro Yasumi, Tadashi Matsubayashi, Tadashi Hosoya, Hiroki Nishikawa, Junya Fujimura, Ryoko Asano, Yuko Sugita, Kenichi Watanabe, Anna Kobayashi, Takuya Endo, Katsuhide Eguchi, Ryuta Nishikomori, Ryuhei Yasuoka, Takaki Asano, Miyako Kanno, Kazuya Hamada, Yuji Fujita, Daisuke Hayashi, Shojiro Watanabe, Takeshi Shiba, Shinsuke Yasuda, Masaaki Mori, Hirokazu Kanegane, Masatoshi Takagi, Masaki Shimizu   +42 more
wiley   +1 more source

Efficacy and safety of conventional disease-modifying antirheumatic drugs in VEXAS syndrome: real-world data from the international AIDA network

Frontiers in Pharmacology
BackgroundVEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is an adult-onset autoinflammatory condition resulting in severe, often treatment-refractory inflammation.
Antonio Vitale, Antonio Vitale, Flavia Leone, Valeria Caggiano, Valeria Caggiano, Andrea Hinojosa-Azaola, Eduardo Martín-Nares, Guillermo Arturo Guaracha-Basañez, Jiram Torres-Ruiz, Perla Ayumi Kawakami-Campos, Pravin Hissaria, Pravin Hissaria, Alicia Callisto, Alicia Callisto, Mark Beecher, Mark Beecher, Lorenzo Dagna, Lorenzo Dagna, Alessandro Tomelleri, Alessandro Tomelleri, Corrado Campochiaro, Corrado Campochiaro, Micol Frassi, Francesca Crisafulli, Franco Franceschini, José Hernández-Rodríguez, Verónica Gómez-Caverzaschi, Olga Araújo, Paolo Sfriso, Sara Bindoli, Chiara Baggio, Jessica Sbalchiero, Jessica Sbalchiero, Jurgen Sota, Jurgen Sota, Abdurrahman Tufan, Ibrahim Vasi, Matteo Piga, Matteo Piga, Alberto Cauli, Alberto Cauli, Maria Antonietta D’Agostino, Amato De Paulis, Amato De Paulis, Ilaria Mormile, Henrique A. Mayrink Giardini, Rafael Alves Cordeiro, Francesco Gavioli, Francesco Gavioli, Giuseppe Lopalco, Florenzo Iannone, Carlomaurizio Montecucco, Sara Monti, Guillermo Ruiz-Irastorza, Guillermo Ruiz-Irastorza, Adriana Soto-Peleteiro, Adriana Soto-Peleteiro, Paola Triggianese, Paola Triggianese, Carmelo Gurnari, Carmelo Gurnari, Ombretta Viapiana, Riccardo Bixio, Rosetta Vitetta, Edoardo Conticini, Edoardo Conticini, Francesco La Torre, Gaafar Ragab, Gaafar Ragab, Ezgi Deniz Batu, Andrés González-García, Mercedes Peña-Rodríguez, Monica Bocchia, Monica Bocchia, Ewa Wiesik-Szewczyk, Karina Jahnz-Rózyk, Alejandra de-la-Torre, Alberto Balistreri, Alberto Balistreri, Bruno Frediani, Bruno Frediani, Claudia Fabiani, Claudia Fabiani, Luca Cantarini, Luca Cantarini   +84 more
doaj   +1 more source

Current status and prospects of diagnosis and treatment of VEXAS syndrome [PDF]

Zhenduanxue lilun yu shijian
VEXAS (Vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome is a recently recognized autoinflammatory disease involving multiple systems, caused by somatic mutations in the ubiquitin-like modifier activating enzyme 1 (UBA1) gene.
QIAN Haozhou, CHANG Chunkang
doaj   +1 more source

Prognostic value of flow cytometry in myelodysplastic neoplasms (MDS): Composition of a FCM‐prognostic score (FCM‐PS) for overall survival

HemaSphere, Volume 10, Issue 2, February 2026.
Abstract Flow cytometry (FCM) is a co‐criterion in myelodysplastic neoplasms (MDS) diagnostics, currently not used for prognostication. This study aimed to develop an FCM‐score predicting overall survival (OS) in MDS to improve early clinical patient prognostication.
Aida Santaolalla, Uta Oelschlaegel, Susann Winter, Shirin Jamshidi, Theresia M. Westers, Katja Sockel, Martin Bornhäuser, Rosa Andres Ejarque, Farzin Farzaneh, Antonella Poloni, Anne‐Sophie Kubasch, Mieke Van Hemelrijck, Arjan A. van de Loosdrecht, Uwe Platzbecker, Shahram Kordasti   +14 more
wiley   +1 more source

VEXAS syndrome: Focus on dermatological manifestations and their histopathological correlate

JEADV Clinical Practice
Background VEXAS ‘Vacuoles, E1 Enzyme, X‐linked, Autoinflammatory, Somatic syndrome’ is a rare autoinflammatory syndrome, first described in October 2020 by Beck et al.
Sofie Engelen, Anne‐Catherine Dens, Frederik Staels, Rik Schrijvers, Daniel Blockmans, Steven Vanderschueren, Albrecht Betrains, F. J. Sherida H. Woei‐A‐Jin, Arno Vanstapel, Franscesca Bosisio, Petra De Haes   +10 more
doaj   +1 more source

Oral mucosal manifestations with identical mutations to the bone marrow in a patient with VEXAS syndrome

Rheumatology &Autoimmunity, Volume 6, Issue 1, Page 60-62, March 2026.
Lilian Vasaitis, Lena Blomstrand, Tatjana Pandzic, Miklos Gulyas, Panagiotis Baliakas, Viktor Ljungström   +5 more
wiley   +1 more source

CO:06:3 | Clinical and laboratory markers for distinguishing VEXAS from Schnitzler's syndrome in male patients with skin involvement: insights from the International AIDA Network Registries

Reumatismo
Background: VEXAS syndrome and Schnitzler’s disease are rare adult-onset autoinflammatory conditions that often present with overlapping clinical and laboratory features, particularly in the early stages.
Società Italiana di Reumatologia
doaj  

Safety and effectiveness of the combination of 5‐azacitidine and ruxolitinib in VEXAS syndrome: A single‐centre experience

British Journal of Haematology, Volume 208, Issue 3, Page 1133-1137, March 2026.
Gregorio Maria Bergonzi, Enrico Cozzo, Alessandro Tomelleri, Costanza Piccolo, Gianluca Scorpio, Carmelo Gurnari, Francesca Romano, Marco Matucci‐Cerinic, Lorenzo Dagna, Massimo Bernardi, Luca Vago, Fabio Ciceri, Corrado Campochiaro, Elisa Diral   +13 more
wiley   +1 more source

VEXAS Syndrome and Substance Use Disorders: A Large‐Scale, Propensity‐Matched, Case‐Control Analysis Revealing Immune‐Mediated Comorbidities

International Journal of Dermatology, Volume 65, Issue 3, Page 584-586, March 2026.
Kritin K. Verma, Kevin T. Nguyen, Daniel P. Friedmann, Helen Chen, Michelle B. Tarbox   +4 more
wiley   +1 more source