Results 21 to 30 of about 2,175 (163)

The tip protein PAAR is required for the function of the type VI secretion system

Microbiology Spectrum, 2023
Bacteria are constantly competing to colonize crowded ecological niches, such as the human gut. The type VI secretion system (T6SS) is a critical bacterial weapon in this warfare.
Solène G. Beauvois, Nicolas Flaugnatti, Marianne Ilbert, Marie Boyer, Esther Gavello-Fernandez, Rémi Fronzes, Dukas Jurėnas, Laure Journet   +7 more
doaj   +1 more source

Genome wide analysis revealed conserved domains involved in the effector discrimination of bacterial type VI secretion system

Communications Biology, 2023
Type VI secretion systems (T6SSs) deliver effectors into target cells. Besides structural and effector proteins, many other proteins, such as adaptors, co-effectors and accessory proteins, are involved in this process.
Caihong Wang, Mingxing Chen, Yuhan Shao, Mengyuan Jiang, Quanjie Li, Lihong Chen, Yun Wu, Shan Cen, Nicholas R. Waterfield, Jian Yang, Guowei Yang   +10 more
doaj   +1 more source

Immunity induced by valine-glycine repeat protein G imparts histoprotection of vital body organs against Acinetobacter baumannii

Journal of Genetic Engineering and Biotechnology, 2022
Background Efforts toward the development of an effective vaccine against Acinetobacter baumannii, one of the most notorious nosocomial pathogens, are still ongoing. In this regard, virulence factors are interesting targets.
Saeed Alipouri, Iraj Rasooli, Mohammad Hossein Ghaini, Abolfazl Jahangiri, Shakiba Darvish Alipour Astaneh, Fatemeh Ramezanalizadeh   +5 more
doaj   +1 more source

VgrG C-terminal tails dictate effector specificity.

, 2021
A, Schematic of tail swapping of VgrG proteins. Structural model of the VgrG complex was generated using the VgrG1 structure of P. aeruginosa as template (PDB: 6H3L) in Chimera.
Ya-Jie Zhao (11778326), Tong-Tong Pei (11778317), Han Luo (302386), Ming-Xuan Tang (11778323), Tao Dong (15551), Hao Li (31608), Ping Xu (122619), Xiaoye Liang (11778314), Hao-Yu Zheng (11778320), Yang Cui (507341)   +9 more
core   +1 more source

Chimeric VgrG proteins restore T6SS secretion in ΔvgrG mutants.

, 2021
A, Competition analysis of double and triple vgrG deletion mutants against E. coli. Survival of E. coli was quantified by serial dilutions on selective medium. When no surviving E.
Ya-Jie Zhao (11778326), Tong-Tong Pei (11778317), Han Luo (302386), Ming-Xuan Tang (11778323), Tao Dong (15551), Hao Li (31608), Ping Xu (122619), Xiaoye Liang (11778314), Hao-Yu Zheng (11778320), Yang Cui (507341)   +9 more
core   +1 more source

Manipulating the type VI secretion system spike to shuttle passenger proteins.

PLoS ONE, 2020
The type VI secretion system (T6SS) is a contractile injection apparatus that translocates a spike loaded with various effectors directly into eukaryotic or prokaryotic target cells.
Sarah Wettstadt, Alain Filloux
doaj   +1 more source

vgrG Gene as a Virulence Factor in Burkholeria cepacia [PDF]

, 2022
Burkholderia cepacia is a gram-negative bacterium responsible for causing onion soft rot disease and has been identified as an infectious agent in people with cystic fibrosis.
Matte, Lexie
core   +1 more source

Systematic dissection of the agrobacterium type VI secretion system reveals machinery and secreted components for subcomplex formation. [PDF]

PLoS ONE, 2013
The type VI secretion system (T6SS) is widely distributed in pathogenic Proteobacteria. Sequence and structural analysis of T6SS reveals a resemblance to the T4 bacteriophage tail, in which an outer sheath structure contracts an internal tube for ...
Jer-Sheng Lin, Lay-Sun Ma, Erh-Min Lai
doaj   +1 more source

Solving the Puzzle: Connecting a Heterologous Agrobacterium tumefaciens T6SS Effector to a Pseudomonas aeruginosa Spike Complex

Frontiers in Cellular and Infection Microbiology, 2020
The type VI secretion system (T6SS) is a contractile injection apparatus that translocates a spike loaded with various effectors directly into eukaryotic and prokaryotic target cells.
Sarah Wettstadt, Erh-Min Lai, Alain Filloux   +2 more
doaj   +1 more source

The Tip of the VgrG Spike Is Essential to Functional Type VI Secretion System Assembly in Acinetobacter baumannii

mBio, 2020
The type VI secretion system (T6SS) is a critical weapon in bacterial warfare between Gram-negative bacteria. Although invaluable for niche establishment, this machine represents an energetic burden to its host bacterium.
Juvenal Lopez, Pek Man Ly, Mario F. Feldman   +2 more
doaj   +1 more source