Results 111 to 120 of about 52,478 (246)

Molecular descriptor driven QSPR modeling of Papp, TEER and Efflux Ratio from Caco‐2 cells using machine learning for various phytochemicals

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The present study aimed to develop and validate quantitative structure–property relationship (QSPR) models for predicting permeability related bioavailability indicators including apparent permeability (Papp), trans‐epithelial electrical resistance (TEER) and efflux ratio (ER) based on molecular descriptors (n = 5003) of 83 ...
Jin‐Woo Kim, Rixing Cong, Jin‐Soo Park, Keunwan Park, Kyungsu Kang, Soon‐Mi Shim   +5 more
wiley   +1 more source

Viñas y corredores ecológicos

ARQ, 2003
Tanto la arquitectura como la arquitectura del paisaje operan a partir de intervenciones que alteran el orden original. En este caso, y por el contrario, se trata de la recuperación de una condición natural perdida: cómo defender la diversidad biológica ...
Teodoro Fernández
doaj  

Bio‐guided fractionation of (9Z)‐5,8,11‐trihydroxyoctadec‐9‐enoic acid from Abelmoschus sagittifolius root as a potent α‐glucosidase inhibitor: An integrated in vitro and in silico study

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Abelmoschus sagittifolius stands out as a valuable medicinal source for developing functional food targeting type 2 diabetes. This study investigated the α‐glucosidase inhibitory potential of an active fraction obtained from A. sagittifolius roots (ASR), enriched in (9Z)‐5,8,11‐trihydroxyoctadec‐9‐enoic acid (OA), using both enzyme ...
Nguyen Phuong Mai, Nguyen Van Quan, Nguyen Dang Duc, Tran Dang Xuan   +3 more
wiley   +1 more source

DERMACLEAR: AI‐Powered Insights Into Four Chronic Inflammatory Skin Diseases in Spain

JEADV Clinical Practice, EarlyView.
Using an AI‐enhanced analysis of electronic health records from nearly 50,000 patients, the DERMACLEAR study provides real‐world insights into the prevalence, clinical complexity, comorbidities and treatment patterns of HS, CU, PsO and AD in Spain.
Ana Giménez‐Arnau, Javier Ortiz de Frutos, Raquel Rivera‐Díaz, Lluís Puig, Jaume Notario Rosa, José Luis López‐Estebaranz, Vicente García‐Patos Briones, Ana Martín‐Santiago, José Ignacio Rojo‐Laguna, Elisabet Fernández‐Martínez, Lara Gómez‐Labrador, Esteban Daudén   +11 more
wiley   +1 more source

Global Matrix 3.0 Physical Activity Report Card Grades for Children and Youth: Results and Analysis From 49 Countries.

Journal of Physical Activity and Health, 2018
Salomé Aubert, Joel D. Barnes, Chalchisa Abdeta, Patrick Abi Nader, A. Adeniyi, Nicolás Aguilar-Farías, D. S. Andrade Tenesaca, J. Bhawra, J. Brazo-Sayavera, G. Cardon, Chen-Kang Chang, Christine Delisle Nyström, Yolanda Demetriou, C. Draper, L. Edwards, A. Emeljanovas, A. Gába, Karla I. Galaviz, S. González, M. Herrera-Cuenca, W. Huang, Izzeldin A E Ibrahim, J. Jürimäe, K. Kämppi, T. Katapally, Piyawat Katewongsa, P. Katzmarzyk, Asaduzzaman Khan, Agata Korcz, Yeonsoo Kim, E. Lambert, Eun-Young Lee, M. Löf, T. Loney, J. López-Taylor, Yang Liu, D. Makaza, Taru Manyanga, Bilyana Mileva, S. Morrison, J. Mota, V. Nyawornota, Reginald Ocansey, J. Reilly, Blanca Roman-Viñas, D. A. Silva, Pairoj Saonuam, J. Scriven, J. Seghers, Natasha Schranz, T. Skovgaard, Melody Smith, M. Standage, G. Starc, G. Stratton, Narayan Subedi, T. Takken, T. Tammelin, C. Tanaka, D. Thivel, D. Tladi, R. Tyler, R. Uddin, Alun Williams, S. Wong, Ching-Lin Wu, Pawel Zembura, M. Tremblay   +67 more
semanticscholar   +1 more source

Matrine Attenuates Neurological Deficits and Neuroinflammation by Inhibiting the HMGB1/RAGE Axis and Ferroptosis in Intracerebral Hemorrhage Mice

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) is a life‐threatening stroke subtype that lacks effective drug therapy. In the context of ICH, neuroinflammation, and ferroptosis are key contributors to secondary brain injury. In this study, we assessed the neuroprotective effects of matrine (MAT) and its mechanism of action involving the HMGB1/RAGE axis in an ...
Pan‐Di Chen, Tao‐Tao Shi, Dan‐Yang Hu, Xiao‐Na Su, Jian‐Xiang Jin, Mao‐Song Chen, Hao Wang, Wei Chen   +7 more
wiley   +1 more source

Assessment of Soil Erosion Over Six Decades in a Long‐Term Experiment Using Fallout 137Cs and RUSLE: A South American Case Study

Land Degradation &Development, EarlyView.
ABSTRACT Soil erosion remains a major global concern affecting agricultural productivity and land sustainability. This study investigates the magnitude and variability of soil erosion in a long‐term experiment (LTE) established in 1963 in Colonia, Uruguay, aiming to compare the performance of the 137Cs tracer technique and the RUSLE model across ...
Marcos Tassano, Mirel Cabrera, Joan Gonzalez, Mario Perez‐Bidegain, Olivier Evrard, Kathrin Grahmann, J. Andrés Quincke   +6 more
wiley   +1 more source

Research Techniques Made Simple: Analysis of Collective Cell Migration Using the Wound Healing Assay.

Journal of Investigative Dermatology, 2017
Ayman Grada, M. Otero-Viñas, Francisco Prieto-Castrillo, Zaidal A Obagi, V. Falanga   +4 more
semanticscholar   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

Pediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu, Boqing Xu, Chunfang Dai, Yayan Pang, Zhifang Dong   +4 more
wiley   +1 more source

Exploring the Reproductive Toxicity of Bisphenol S Through a Network Toxicology and Molecular Docking Analysis

Pediatric Discovery, EarlyView.
Utilizing network toxicology, molecular docking, and dynamic simulations to investigate the potential reproductive toxicity of bisphenol S (BPS). ABSTRACT The aim of this study was to investigate the potential reproductive toxicity of bisphenol S (BPS) and the related molecular mechanisms through a network toxicology approach.
Siyuan Wang, Yan Fu, Xu Huang, Qitong Guo, Xiangqin Zheng, Shengde Wu, Lianju Shen, Guanghui Wei   +7 more
wiley   +1 more source