Results 121 to 130 of about 52,478 (246)

Unsaturated biobased polyesters from bicyclic α‐pinene‐based diols

Polymer International, EarlyView.
We present the synthesis of four biosourced unsaturated polyesters made from chiral terpene‐based diols and esters of renewable diacids. The resulting materials harbor a bicyclic pinene ring in their backbones which leads to enhanced thermal properties while still conferring susceptibility to enzyme hydrolysis for chains having a cis alkene.
Ganapathy Ranjani, Shengwei Sun, Erik Sundén, Diana Bernin, Per‐Olof Syrén   +4 more
wiley   +1 more source

From traditional practice to unsustainable exploitation: Fruit overharvesting on the endangered relict palm Jubaea chilensis

PLANTS, PEOPLE, PLANET, EarlyView.
Overharvesting of wild edible plants poses a growing threat to plant populations worldwide, particularly for slow‐growing species with limited regeneration. We quantified fruit extraction from the third‐largest known population of Jubaea chilensis—an endangered palm endemic to Chile—modeled the critical harvest threshold, and assessed consumer ...
Sebastián Cordero, Francisca Gálvez, Marisol Arriagada‐Honores, Andrés Jesús Garrido, Daniela Paredes‐Muñoz, Bastián Fuentes‐Valdés, Fernanda Torres‐Cifuentes, Francisco E. Fontúrbel   +7 more
wiley   +1 more source

The Mycobacterium tuberculosis Rv0132c Gene Product Mtb‐FGD2 Can Act as an F420‐Dependent Glucose Dehydrogenase

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The role of the cell envelope‐associated Rv0132c/FGD2 from Mycobacterium tuberculosis has long been a subject of debate. Importantly, FGD2 is found only in pathogenic mycobacteria, making it a potential drug target. While some suggest it functions as a glucose‐6‐phosphate dehydrogenase, others propose it acts instead as an F420‐dependent ...
Adewale V. Aderemi, Matthew Snee, Richard B. Tunnicliffe, Linus O. Johanissen, Matthew J. Cliff, Colin W. Levy, Derren J. Heyes, Marina Golovanova, Thomas A. Jowitt, Sam Hay, Andrew W. Munro, Jonathan P. Waltho, David Leys   +12 more
wiley   +1 more source

Dehydrocostus Lactone Suppresses Hepatocellular Carcinoma by Inhibiting Protein Tyrosine Kinase‐7 Mediated β‐Catenin Signaling

Phytotherapy Research, EarlyView.
Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan, Junhui Li, Yu Qiao, Yuwen Zhong, Xuecheng Ge, Yaoshuai Zhang, Zishu Wang, Feng Qian, Weixin Ren   +8 more
wiley   +1 more source

Betulinic Acid Enema Alleviates Colitis by Targeting Vitamin D Receptor to Protect the Intestinal Mucosal Barrier and Modulate Mucosa‐Associated Microbiota

Phytotherapy Research, EarlyView.
ABSTRACT Ulcerative colitis (UC) is a chronic inflammatory disease of the colon with limited effectiveness and safety of current drug therapies. Betulinic acid (BA) is a naturally occurring pentacyclic triterpenoid present in traditional Chinese medicines used clinically as retention enemas for UC, but its direct effects and mechanisms remain unclear ...
Lina Dong, Yuanxia Gao, Qian Li, Guangxin Chen, Dong Yang, Liping Zhao, Xiaojing Liu, Shumei Lin   +7 more
wiley   +1 more source

An overview of antimicrobial peptides and the latest advances in their development

Expert Opinion on Biological Therapy, 2017
J. Sierra, E. Fusté, F. Rabanal, T. Vinuesa, M. Viñas   +4 more
semanticscholar   +1 more source

Isolation, Insularity and Resilience: A Review of the Geophysical, Socioeconomic, and Environmental Vulnerabilities of Gran Canaria and Lesvos Islands for Policy Interventions to Global Change

Sustainable Development, EarlyView.
ABSTRACT The dynamic nature of small islands being geographically isolated and their perceived connectedness with global networks complicates research attempts to draw general conclusions on whether insularity leads to marginalization or strengthens their resilience for sustainable development.
Toheeb Lekan Jolaosho, Mazen Marouani, Takwa Boughanmi   +2 more
wiley   +1 more source

Assessing Eco‐Efficiency in Municipal Solid Waste Management Integrating Heterogeneity: A Latent Class Stochastic Frontier Analysis

Sustainable Development, EarlyView.
ABSTRACT The measurement of eco‐efficiency in the municipal solid waste (MSW) sector has garnered significant attention due to the substantial environmental impacts of unsustainable MSW management and the high operational costs associated with public service provision.
Ramon Sala‐Garrido, Alexandros Maziotis, Maria Molinos‐Senante   +2 more
wiley   +1 more source

Delafloxacin suppresses DEPDC1 expression and induces G2/M arrest in non‐small cell lung cancer cells: A drug repurposing study

Smart Molecules, EarlyView.
This study presents Delafloxacin repurposed as a DEPDC1‐targeting therapeutic aiming to suppress lung cancer progression. It highlights a novel strategy for lung cancer treatment with potential clinical applications. Abstract Emerging evidence highlights the oncogenic role of the Dishevelled, Egl‐10, and Pleckstrin domains containing 1 (DEPDC1) gene in
Noman Ali, Farishta Shafiq, Mishal Iftikhar, Muhammad Shahzad Zafar, Muhammad Shoaib   +4 more
wiley   +1 more source

Correction: Understanding Biologics in CRSwNP: Related Events and Insights. [PDF]

Curr Allergy Asthma Rep
Izquierdo-Domínguez A, Al-Salloom Z, Viñas M, Mullol J, Alobid I.   +4 more
europepmc   +1 more source