Results 191 to 200 of about 52,478 (246)

Think Globally, Act Locally: A Glocal Approach Based on the Regional Report Cards From Spain in the AHKGA Global Matrix 4.0. [PDF]

open access: yesChild Care Health Dev
Brazo-Sayavera J   +8 more
europepmc   +1 more source

Stereochemical Modulation of Palladacyclopentadienyl Complexes Bearing Diphosphine Ligands: A Key to Enhanced DNA Interaction and Anticancer Activity

open access: yesEuropean Journal of Inorganic Chemistry, Volume 29, Issue 16, 4 June 2026.
A modular library of structurally robust palladacyclopentadienyl Pd(II) complexes bearing achiral and chiral diphosphines was developed, revealing a strong influence of diphosphine design and ligand chirality on cytotoxicity and selectivity against ovarian cancer cells, including platinum‐resistant models.
Stefania Mautone   +7 more
wiley   +1 more source

Nanoplastics, Liver Injury, and Oxidative Mechanisms: Translating Animal Models Into Human Risk Assessment. [PDF]

open access: yesCureus
Ruiz-Ramos R   +6 more
europepmc   +1 more source

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

open access: yesAdvanced Science, Volume 13, Issue 32, 9 June 2026.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun   +7 more
wiley   +1 more source

Densely-functionalized bicyclic cyclopentanones by combined photoinduced 6-<i>endo-trig</i> Giese additions and mild aldol cyclizations.

open access: yesOrg Chem Front
Viñas-Lóbez J   +7 more
europepmc   +1 more source

Copper Depletion Nanoparticles Potentiate Cancer Immunotherapy by Avoiding Innate and Adaptive Immune Resistance

open access: yesAdvanced Science, Volume 13, Issue 32, 9 June 2026.
A mitochondria‐targeted copper depletion nanoplatform (CYN‐CDA@Alb) was developed to selectively disrupt tumor mitochondria copper, which then reprogrammed the tumor immune microenvironment by depressing PD‐L1 and CD47 expression simultaneously. By doing this, CYN‐CDA@Alb reversed radiotherapy‐induced immune tolerance, showing the potential usage of ...
Zaigang Zhou   +10 more
wiley   +1 more source

MAPK ERK5 is a novel regulator of MHC-I in cancer cells. [PDF]

open access: yesCell Commun Signal
Viñas-Casas M, Lizcano JM.
europepmc   +1 more source

Decoding Aquaculture's Future: A Review of Molecular Docking and Simulation in Enhancing Growth and Disease Resistance

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 3, June 2026.
ABSTRACT Aquaculture has overtaken capture fisheries as the main source of aquatic animal protein, marking a critical step in global food security. Yet, rapid intensification faces major challenges, including disease outbreaks, environmental degradation, and dependence on wild‐caught fish for feed.
Suvadip Ghara   +8 more
wiley   +1 more source

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