Results 151 to 160 of about 946,904 (313)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Guidezilla extension catheter for percutaneous interventional therapy of complex lesions via a transradial approach: Case series from a single-center experience

open access: yes, 2018
   Background: Guide catheter extension systems have become one of the most powerful tools for address­ing complex lesions during percutaneous coronary intervention (PCI), but data on a new-generation rapid exchange extension catheter — the Guidezilla ...
Zhou, Sheng-hua; Department of Cardiology, Second Xiangya Hospital, Central South University   +5 more
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Accurate Asthma-COPD Overlap Classification via Deep Transfer Learning in Medical Image Segmentation

open access: yesInternational Journal of COPD
Weijie Ye,1,* Dieyi Mo,2,* Yubin Yang3 1Department of Respiratory, Guangzhou Panyu District Maternal and Child Health Hospital (Affiliated Hospital Group of Guangdong Medical University Panyu HeXian Memorial Hospital), Guangzhou, People’s
Ye W, Mo D, Yang Y
doaj  

The Q-Codes classification available via URI

open access: yes, 2017
Accès direct en ligne aux fiches terminologiques de la classification Q-Codes. Chaque code est publié via une URI. Classification complémentaire à la CISP-2, contextuelle de l'activité de médecine générale, disponible via des URI.Direct access to the ...
Darmoni, Stefan   +2 more
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Drum Transcription via Classification of Bar-level Rhythmic Patterns [PDF]

open access: yes, 2014
acceptedMatthias Mauch is supported by a Royal Academy of Engineering Research ...
Mauch, M   +3 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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