Results 111 to 120 of about 1,387,486 (309)
Agriculture Viability Grants Program : [application] 2008
, 2008 Annual; Description based on: 2007; title from PDF cover (publisher's web site, viewed Jan. 15, 2008).; "Farm Viability Grant, Farm Transition Grant."; Funding for the State of Connecticut agriculture viability grants was established in 2005 through ...
Agriculture Viability Grants Program (Conn.)
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Back to basics: biophysical methods in tissue viability research [PDF]
, 2013 The continued growth of research in the areas of tissue viability and wound care has led to the development of an equally diverse range of techniques to assess wounds and provide some quantitative measure of healing. These range from highly sophisticated
Voegeli, David +3 more
core +1 more source
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Examination of the lower limb in high risk patients
, 2000 When 'at risk' patients say that their feet are killing them, they may be right. Diabetes mellitus accounts for 50 to 70% of all nontraumatic amputations with a three year survival rate of those who undergo a lower limb amputation of 50%.
Carline, Tom, Santos, Derek
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
The changing role of the tissue viability nurse: an exploration of this multifaceted post
, 2014 This article explores the role of the tissue viability nurse in the UK and discusses the diversity of the role and key attributes and skills required to run a successful service.
Atkin, Leanne +3 more
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Cross-examination of agroecology and viability in agro-sylvo-pastoral systems in Western Burkina Faso [PDF]
International audiencehis study aimed to examine the correlations between the agroecological status of farms and their viability in agro-sylvo-pastoral systems located in the savannah areas of West Africa.
Vall, Eric +8 more
core +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source