Results 91 to 100 of about 1,581,972 (289)
Differential games through viability theory : old and recent results. [PDF]
This article is devoted to a survey of results for differential games obtained through Viability Theory. We recall the basic theory for differential games (obtained in the 1990s), but we also give an overview of recent advances in the following areas ...
Saint-Pierre, Patrick +2 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
, 2018 Egg-to-adult viability data from D. melanogaster (the Dahomey laboratory-adapted population), measured in vials. Focal F is number of eclosed females and Focal M number of eclosed males.
Maguire-Baxter, Jack +9 more
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Effect of storage on seed viability and vigour in different Ethiopian wheat and maize cultivars [PDF]
, 2000 English: Seed viability and vigour loss during storage, is one of the several factors limiting crop yield in Ethiopia. Ambient storage conditions (high temperature and relative humidity) as well as high moisture content during storage are considered ...
Engida, Mekonnen Beyene
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Agriculture Viability Grants Program [application]. 2009.
, 2009 Annual; "Farm Viability Grant, Farm Transition Grant."; Description based on: 2007; title from PDF cover (publisher's Web site, viewed Jan. 15, 2008).; Funding for the State of Connecticut agriculture viability grants was established in 2005 through ...
Agriculture Viability Grants Program (Conn.)
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Agriculture Viability Grants Program [application]. 2012.
, 2012 Annual; "Farm Viability Grant, Farm Transition Grant."; Funding for the State of Connecticut agriculture viability grants was established in 2005 through Public Act 05-228, an Act Concerning Farm Land Preservation, Land Protection, Affordable Housing and
Agriculture Viability Grants Program (Conn.)
core
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source