Results 81 to 90 of about 1,581,972 (289)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Effects of Trehalose and Fetal Bovine Serum on Cryopreservation of HBL-100 Human Breast Cells
Zhileng xuebao, 2017 Establishing a high-quality biobank is very important, but the cryoprotective agent (CPA) type and concentration have a considerable influence on the cryopreservation effect.
Wang Meixia +3 more
doaj
Agriculture Viability Grants Program : [application] 2018.
, 2018 Annual; "Farm Viability Grant, Farm Transition Grant."; Funding for the State of Connecticut agriculture viability grants was established in 2005 through Public Act 05-228, an Act Concerning Farm Land Preservation, Land Protection, Affordable Housing and
Agriculture Viability Grants Program (Conn.)
core
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Viability of Lactobacillus acidophilus LA-5 and Bifidobacterium bifidum BB-12 in Rice Pudding
Mljekarstvo, 2010 The purpose of this study was to determine the survival of two probiotic micro-organisms (Lactobacillus acidophilus LA-5 and Bifidobacterium bifidum BB-12) in a rice pudding, the impact of these bacteria on hygienic quality, and to verify the ...
Tulay Ozcan +4 more
doaj
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Effect of using different probiotic cultures on properties of Torba (strained) yoghurt
Mljekarstvo, 2010 The viability of Lactobacillus casei LAFTI® L26, Bifidobacterium animalis subsp. lactis LAFTI® B94 and Lactobacillus acidophilus LAFTI® L10, their proteolytic activities and effects on chemical, textural and sensory properties of Torba yoghurts were ...
Harun Kesenkaş
doaj
Ovozoa: Journal of Animal ReproductionThis study aims to determine the best dose of basil leaf extract to add to AndroMed® semen extender to improve spermatozoa quality after freezing and thawing. This study used healthy, normal four-year-old Simmental bulls with good libido. The sample used
Aditya Irawan +8 more
doaj +1 more source
Current Perspectives on Viable but Non-Culturable (VBNC) Pathogenic Bacteria
Frontiers in Public Health, 2014 Under stress conditions, many species of bacteria enter into starvation mode of metabolism or a physiologically viable but non-culturable (VBNC) state.
Thandavarayan eRamamurthy +3 more
doaj +1 more source