Results 71 to 80 of about 1,026,267 (263)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Viability of Lactobacillus acidophilus LA-5 and Bifidobacterium bifidum BB-12 in Rice Pudding
Mljekarstvo, 2010 The purpose of this study was to determine the survival of two probiotic micro-organisms (Lactobacillus acidophilus LA-5 and Bifidobacterium bifidum BB-12) in a rice pudding, the impact of these bacteria on hygienic quality, and to verify the ...
Tulay Ozcan +4 more
doaj
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Effect of using different probiotic cultures on properties of Torba (strained) yoghurt
Mljekarstvo, 2010 The viability of Lactobacillus casei LAFTI® L26, Bifidobacterium animalis subsp. lactis LAFTI® B94 and Lactobacillus acidophilus LAFTI® L10, their proteolytic activities and effects on chemical, textural and sensory properties of Torba yoghurts were ...
Harun Kesenkaş
doaj
Ovozoa: Journal of Animal ReproductionThis study aims to determine the best dose of basil leaf extract to add to AndroMed® semen extender to improve spermatozoa quality after freezing and thawing. This study used healthy, normal four-year-old Simmental bulls with good libido. The sample used
Aditya Irawan +8 more
doaj +1 more source
Current Perspectives on Viable but Non-Culturable (VBNC) Pathogenic Bacteria
Frontiers in Public Health, 2014 Under stress conditions, many species of bacteria enter into starvation mode of metabolism or a physiologically viable but non-culturable (VBNC) state.
Thandavarayan eRamamurthy +3 more
doaj +1 more source
ON RELATIVE VIABILITY AND REPLACEMENT [PDF]
Proceedings of the National Academy of Sciences, 1963 A type of replacement exists that could seriously alter the outcome of studies on the viability of irradiated x chromosomes. Conditions under which the replacement could occur were defined, and a search was made for thls kind of replacement by comparing the number of Drosophila melanogaster of various genotypes emerging in comparable lethal and ...
openaire +2 more sources
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source