Results 61 to 70 of about 1,387,486 (309)
Background: Agave potatorum reproduces mainly through seeds is widely collected for the mezcal production, and there is currently a marked decrease in their wild populations.
Yolanda Donají Ortiz-Hernández +4 more
doaj +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Financial Viability of Cocoa Agroforestry Management Technologies in Ghana
This dataset was produced to study financial viability of cocoa agroforestry management technology in Ghana. Isaac Nunoo, a graduate student in Department of Agricultural Economics, Agribusiness and Extension at the University of Kwame Nkrumah University
Nunoo, Isaac
core +1 more source
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Sustainability, optimality, and viability in the Ramsey model [PDF]
The Ramsey model of economic growth is revisited from the point of view of viability compared to optimality. A viable state is a state from which there exists at least one trajectory in capital, consumption, and reproduction that remains in the set of ...
Raouf Boucekkine, Noël Bonneuil
core +2 more sources
Dahi is a fermented milk product containing probiotic lactic acid bacteria. This study aimed to isolate, identify, and characterize lactic acid-producing bacteria from native Dahi and evaluate their viability in orange juice using natural prebiotics ...
Fahmida Akter +6 more
doaj +1 more source
Flow invariance for perturbed nonlinear evolution equations
Let X be a real Banach space, J=[0,a]⊂R, A:D(A)⊂X→2X\ϕ an m-accretive operator and f:J×X→X continuous. In this paper we obtain necessary and sufficient conditions for weak positive invariance (also called viability) of closed sets K⊂X for the evolution ...
Dieter Bothe
doaj +1 more source
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Surfactant Protein D (SP-D), a pattern recognition innate immune molecule, has been implicated in the immune surveillance against cancer. A recent report showed an association of decreased SP-D expression in human prostate adenocarcinoma with an ...
Gargi Thakur +10 more
doaj +1 more source

