Results 61 to 70 of about 1,387,486 (309)

Varietal and germinative characterization of Agave potatorum (Asparagaceae) seeds with different origins

open access: yesBotan‪ical Sciences, 2018
Background: Agave potatorum reproduces mainly through seeds is widely collected for the mezcal production, and there is currently a marked decrease in their wild populations.
Yolanda Donají Ortiz-Hernández   +4 more
doaj   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1626-1642, June 2026.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Financial Viability of Cocoa Agroforestry Management Technologies in Ghana

open access: yes, 2013
This dataset was produced to study financial viability of cocoa agroforestry management technology in Ghana. Isaac Nunoo, a graduate student in Department of Agricultural Economics, Agribusiness and Extension at the University of Kwame Nkrumah University
Nunoo, Isaac
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Sustainability, optimality, and viability in the Ramsey model [PDF]

open access: yes
The Ramsey model of economic growth is revisited from the point of view of viability compared to optimality. A viable state is a state from which there exists at least one trajectory in capital, consumption, and reproduction that remains in the set of ...
Raouf Boucekkine, Noël Bonneuil
core   +2 more sources

Ameliorated Viability of Lactic Acid Bacteria in Fruit Juice Isolated from Indigenous Dahi with Prebiotics (Asparagus falcatus and Zingiber officinale)

open access: yesTurkish Journal of Agriculture: Food Science and Technology
Dahi is a fermented milk product containing probiotic lactic acid bacteria. This study aimed to isolate, identify, and characterize lactic acid-producing bacteria from native Dahi and evaluate their viability in orange juice using natural prebiotics ...
Fahmida Akter   +6 more
doaj   +1 more source

Flow invariance for perturbed nonlinear evolution equations

open access: yesAbstract and Applied Analysis, 1996
Let X be a real Banach space, J=[0,a]⊂R, A:D(A)⊂X→2X\ϕ an m-accretive operator and f:J×X→X continuous. In this paper we obtain necessary and sufficient conditions for weak positive invariance (also called viability) of closed sets K⊂X for the evolution ...
Dieter Bothe
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Human SP-D Acts as an Innate Immune Surveillance Molecule Against Androgen-Responsive and Androgen-Resistant Prostate Cancer Cells

open access: yesFrontiers in Oncology, 2019
Surfactant Protein D (SP-D), a pattern recognition innate immune molecule, has been implicated in the immune surveillance against cancer. A recent report showed an association of decreased SP-D expression in human prostate adenocarcinoma with an ...
Gargi Thakur   +10 more
doaj   +1 more source

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