Results 141 to 150 of about 1,940,966 (390)
Multi‐omics profiling reveals key factors involved in Ewing sarcoma metastasis
Molecular Oncology, Volume 19, Issue 4, Page 1002-1028, April 2025.Using a mouse model that recapitulates the spread of tumor cells within the body, we have profiled paired tumors and metastasis samples using a multiomics approach combining different layers of biological information. We identified key genes that drive metastasis in Ewing sarcoma.
Mariona Chicón‐Bosch +11 more
wiley +1 more source
FACTORS AFFECTING THE VIABILITY AND GERMINATION BEHAVIOR OF CONIFEROUS SEED: Part III: COMMERCIAL PROCESSING AND TREATMENTS SIMILAR TO PROCESSING, PSEUDOTSUGA MENZIESII (MIRB.) FRANCO, AND OTHER SPECIES [PDF]
, 1958 G. S. Allen
openalex +1 more source
KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells
Molecular Oncology, Volume 19, Issue 5, Page 1404-1421, May 2025.We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock +10 more
wiley +1 more source
Recent advances and viability in biofuel production
, 2021 Shweta J. Malode +4 more
semanticscholar +1 more source
Viability Kernel for Ecosystem Management Models [PDF]
arXiv, 2009 We consider sustainable management issues formulated within the framework of control theory. The problem is one of controlling a discrete--time dynamical system (e.g. population model) in the presence of state and control constraints, representing conflicting economic and ecological issues for instance.
arxiv
ERYTHROCYTE PRESERVATION. V. RELATIONSHIP BETWEEN CHEMICAL CHANGES AND VIABILITY OF STORED BLOOD TREATED WITH ADENOSINE 1 [PDF]
, 1955 Beverly W. Gabrio +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy +12 more
wiley +1 more source
Diffusion-based Planning with Learned Viability Filters [PDF]
arXivDiffusion models can be used as a motion planner by sampling from a distribution of possible futures. However, the samples may not satisfy hard constraints that exist only implicitly in the training data, e.g., avoiding falls or not colliding with a wall. We propose learned viability filters that efficiently predict the future success of any given plan,
arxiv
Molecular Oncology, Volume 19, Issue 5, Page 1452-1470, May 2025.Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti +8 more
wiley +1 more source