Results 211 to 220 of about 1,940,966 (390)

A potential tumor suppressor role of PLK2 in glioblastoma

FEBS Open Bio, Volume 15, Issue 5, Page 856-866, May 2025.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia, Peirui Wang, Hua Xiao, Qishan Ran, Yan Li, Shengtao Yao   +5 more
wiley   +1 more source

Advancing Probiotic Delivery in Functional Yogurt: Encapsulation in Prebiotic-Based Matrices. [PDF]

Foods
Laina KT, Drosou C, Frakolaki G, Krokida M.   +3 more
europepmc   +1 more source

EFFECT OF CHANGE OF TEMPERATURE UPON THE VIABILITY OF A THERMOPHILIC BACTERIUM

, 1958
Jun Hirano, YOSHIHIKO MUTOH, Mizuho Kitamura, SHOHGO ASAI, ISAMU NAKAJIMA, Akihiro Takamiya   +5 more
openalex   +2 more sources

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, Volume 15, Issue 5, Page 773-792, May 2025.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

Low Dose Methotrexate Has Divergent Effects on Cycling and Resting Human Hematopoietic Stem and Progenitor Cells. [PDF]

Clin Transl Sci
Lora M, Ménard HA, Nijnik A, Langlais D, Hudson M, Colmegna I.   +5 more
europepmc   +1 more source

Studies in the Recovery of Viable Cells of Freeze-Dried Serratia marcescens1

, 1957
Aaron E. Wasserman, William J. Hopkins
openalex   +1 more source

Studies on salt action. I. Effect of calcium and sodium salts upon the viability of the colon bacillus in water [PDF]

, 1918
C.‐E. A. Winslow, I. S. Falk
openalex   +1 more source

Acacetin reduces endoplasmic reticulum stress through the P‐eNOS/PERK signaling pathway to attenuate MGO‐induced vascular endothelial cell dysfunction

FEBS Open Bio, Volume 15, Issue 5, Page 793-809, May 2025.
We investigated a potential protective effect of acacetin, a naturally occurring flavonoid, against methylglyoxal (MGO)‐induced endothelial dysfunction in human umbilical vein endothelial cells and its mechanism of action. Acacetin can could inhibit MGO‐induced intracellular calcium ion influx, enhance the expression levels of phosphorylated ...
Zhen Zhang, Kaien Hu, Zhaohui Fang, Sihai Wang, Jie Chen, Dengke Yin, Caiyun Zhang, Gefei Ma   +7 more
wiley   +1 more source

Integrated transcriptomics and metabolomics to explore the mechanisms of Elaeagnus mollis diels seed viability decline. [PDF]

BMC Genomics
Ruifen R, Jiayi G, Zhe J, Shuhui D, Xiuyun Y.   +4 more
europepmc   +1 more source

Hydrogen sulfide repairs testicular damage induced by heat stress in rats

FEBS Open Bio, EarlyView.
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo, Yupeng Yin, Susu Guo, Xiaoyan Chen, Suyan Xie, Shiqin Chen, Yan Huang   +6 more
wiley   +1 more source