Results 21 to 30 of about 119 (106)

Andar a pé em São Paulo:

Pós: Revista do Programa de Pós-Graduação em Arquitetura e Urbanismo da FAUUSP, 2021
Em São Paulo, o ato de andar a pé embute um paradoxo: apesar de as viagens a pé serem o meio mais usado de deslocamento, as condições urbanas apresentam um quadro bastante desafiador para o pedestre — infraestrutura de caminhabilidade pouco adequada ...
Mauro Sérgio Procópio Calliari
doaj  

Avaliação do ganho na redução de CO2 devido a disponibilidade de um sistema metroviário: Aplicação no Metrô do Rio de Janeiro

Transportes, 2013
A emissão de CO2 pelos sistemas metroviários é geralmente muito pequena. Haveria maior emissão, caso seus passageiros não dispusessem do sistema e tivessem que utilizar outros modos de transporte.
Carlos Eduardo Sanches de Andrade, Marcio de Almeida D'Agosto, Ilton Curty Leal Junior   +2 more
doaj   +1 more source

Sex‐specific differences in mortality and neurocardiac interactions in the Kv1.1 knockout mouse model of sudden unexpected death in epilepsy (SUDEP)

The Journal of Physiology, Volume 604, Issue 16, Page 6731-6751, 15 August 2026.
Abstract figure legend The Kcna1 knockout mouse model of sudden unexpected death in epilepsy (SUDEP) exhibits sex‐specific differences in SUDEP risk. Female mice exhibit a lower SUDEP risk than males, despite similar seizure characteristics and interictal cardiac function across sexes.
Kelsey Paulhus, Praveen Kumar, Kelly Kneale, T. Noah Hutson, Nicole M. Gautier‐Hall, Deng‐Shan Shiau, Megan Watts, Krystle Trosclair, Hemangini A. Dhaibar, Paari Dominic, Leonidas Iasemidis, Edward Glasscock   +11 more
wiley   +1 more source

Abi3S212F Alzheimer's disease variant alters plaque structure and disrupts microglia

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract BACKGROUND Genetic variants affecting microglial function can influence Alzheimer's disease (AD) risk, yet the underlying mechanisms remain unclear. The AD‐associated ABI3S209F (Abi3S212F in mouse) variant regulates cytoskeletal dynamics, but its in vivo impact on pathology is unknown. METHODS: An Abi3S212F mouse was developed and crossed with
Claire A. Butler, Min Sung Gee, Katie O'Gara, Giedre Milinkeviciute, Celia Da Cunha, Shimako Kawauchi, Yueh‐Hao Lu, Nellie Kwang, Kate I. Tsourmas, Christiana Prekopa, Zechuan Shi, Heidi Yahan Liang, Sherilyn D. Collins, Zachary A. Pashkutz, Jenna A. Sanchez, Kai‐Xuan Shi, Amber D. Walker, Shuling Wang, Maigan L. A. Wong, Karina Genaro, Jonathan Neumann, Angela Gomez‐Arboledas, Duc M. Duong, Nicholas T. Seyfried, Andrea J. Tenner, Frank M. LaFerla, Ali Mortazavi, Vivek Swarup, Grant R. MacGregor, Kim N. Green   +29 more
wiley   +1 more source

Cardiac‐specific Kv1.1 deficiency alters cardiomyocyte electrophysiology without modifying overall cardiac function or arrhythmia susceptibility

Experimental Physiology, Volume 111, Issue 3, Page 1120-1133, 1 March 2026.
Abstract The leading cause of epilepsy‐related mortality is sudden unexpected death in epilepsy (SUDEP), resulting from seizure‐induced cardiorespiratory arrest by mechanisms that remain unresolved. Mutations in ion channel genes expressed in both brain and heart represent SUDEP risk factors because they can disrupt neural and cardiac rhythms ...
Kelsey Halvorson, Man Si, Krystle Trosclair, Ellen Aughenbaugh, Maxine Parkinson, Nicole M. Gautier‐Hall, Megan Watts, Frederica Kizek, Md. Shenuarin Bhuiyan, Paari Dominic, Kathryn A. Hamilton, Edward Glasscock   +11 more
wiley   +1 more source

Amniotic Membrane and Mesenchymal Stem Cell Coalescence for Islet Transplantation in Experimental Diabetes in Rats

Journal of Tissue Engineering and Regenerative Medicine, Volume 2025, Issue 1, 2025.
Aims The aim of this study is to investigate the effects of islet cells and mesenchymal stem cells transferred together in the amniotic membrane (AM) in order to preserve the viability and functionality of islet cells on the success of islet transplantation in diabetes mellitus–induced rats.
Meral Tiryaki, Nurgul Atmaca, Ferda Pinarli, Gulbahar Boyuk Ozcan, Mehmet Sedat Feyat, Sercan Mercan, Aynur Albayrak, Hasan Tarik Atmaca, Cherie Stabler   +8 more
wiley   +1 more source

The Abca7V1613M variant reduces Aβ generation, plaque load, and neuronal damage

Alzheimer's &Dementia, Volume 20, Issue 7, Page 4914-4934, July 2024.
Abstract BACKGROUND Variants in ABCA7, a member of the ABC transporter superfamily, have been associated with increased risk for developing late onset Alzheimer's disease (LOAD). METHODS CRISPR‐Cas9 was used to generate an Abca7V1613M variant in mice, modeling the homologous human ABCA7V1599M variant, and extensive characterization was performed ...
Claire A. Butler, Adrian Mendoza Arvilla, Giedre Milinkeviciute, Celia Da Cunha, Shimako Kawauchi, Narges Rezaie, Heidi Y. Liang, Dominic Javonillo, Annie Thach, Shuling Wang, Sherilyn Collins, Amber Walker, Kai‐Xuan Shi, Jonathan Neumann, Angela Gomez‐Arboledas, Caden M. Henningfield, Lindsay A. Hohsfield, Mark Mapstone, Andrea J. Tenner, Frank M. LaFerla, Ali Mortazavi, Grant R. MacGregor, Kim N. Green   +22 more
wiley   +1 more source

Mobilidade de idosos e estrutura familiar

Oculum Ensaios
O presente estudo evidencia os principais resultados de uma investigação que se propôs a analisar a mobilidade da população idosa na Região Metropolitana de Belo Horizonte e sua articulação às estruturas domiciliares existentes.
Eugênia Dória Viana Cerqueira, Ana Marcela Ardila Pinto, Daniela Antunes Lessa, Ana Clara Carreira, Júlia Ribeiro Borges   +4 more
doaj   +1 more source

A study of the life history of Brazilian sardines, Sardinella aurita: I. Distribution and abundance of sardine eggs in the region of Ilha Grande, Rio de Janeiro

Brazilian Journal of Oceanography, 1971
Distribution and abundance of sardine eggs in the Ilha Grande region, Rio de Janeiro, Brazil, were studied during five cruises for the 1969 1970 period. Using the shipboard fertilized eggs and the planktonic eggs, morphological descriptions of Brazilian ...
Yasunobu Matsuura
doaj   +1 more source

Fatores que afetam as decisões individuais de realizar viagens a pé: estudo qualitativo

Transportes, 2010
Este trabalho apresenta uma pesquisa qualitativa desenvolvida com o objetivo de identificar os fatores que influenciam a decisão de realizar viagens a pé. Para o desenvolvimento do trabalho foi utilizada a técnica de entrevistas individuais, que permitiu
Ana Margarita Larrañaga, José Luis Duarte Ribeiro, Helena Beatriz Betella Cybis   +2 more
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